Prem Kumar Essgir1,2* and Nanda Kishore P2
1Assistant Professor, School of Allied Health Sciences, Mallareddy University,
2Consultant Transfusion Medicine, Yashoda Super Speciality Hospitals, Somajiguda, Hyderabad, India
*Corresponding Author: Prem Kumar Essgir, Assistant Professor, School of Allied Health Sciences, Mallareddy University, Hyderabad, India.
Received: January 19, 2022; Published: February 11, 2022
Introduction: Rare Bombay phenotype was first reported in Bombay, India by Bhende and Bhatia in 1952. Bombay phenotype is characterized by absence of H, A and B antigens on red cells and in secretions, while plasma contains anti A, anti B and anti H. Genetically Bombay Oh phenotype individuals are termed as homozygous hh/sese.
Methodology: Blood grouping (ABO and RhD) was done in our blood bank by semi-automated Column Agglutination Technology (CAT) as well as Tube agglutination method and performed Adsorption Inhibition Test using saliva (tube method) for confirming secretor status.
Results: A young 21years male voluntary donor donated blood at our blood bank. The ABO Grouping and RhD typing with serum grouping Indicated Bombay Oh RhD Positive group. Further tests done were: Direct Coombs Test/Indirect Coombs Test by 3 cell panel and Adsorption Inhibition Test by using saliva, which confirmed the Bombay blood group.
Conclusion: To identify Bombay Oh Blood group we recommend complete immunohematology workup (Blood Group: Forward and Reverse with Auto control) using standardised agglutination technologies combined with saliva testing for secretary status (with controls).
Keywords: Bombay Blood Group, ABO RhD, Column Agglutination Technology, Saliva Testing, Immunohematology, Direct Coombs Test, Indirect Coombs Test
Citation: Prem Kumar Essgir and Nanda Kishore P. “Identification of Rare Bombay Phenotype by Immunohematology Workup: A Case Report”.Acta Scientific Medical Sciences 6.3 (2022): 05-07.
Copyright: © 2022 Prem Kumar Essgir and Nanda Kishore P. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.