Abstract

In developing countries, micronutrient deficiencies are of major impact on children development. Zinc is among the micronutrient which is supposed to play an important role in children development, including both growth and cognitive performance. Although the evidence for the role of zinc in cognitive development though animals’ studies is proved, evidence from human studies is still not conclusive. The association between dietary zinc status and cognitive functions through epidemiological studies, remains elusive. This review is summarizing current literature and epidemiological studies that investigated the association between zinc intake, through diet or supplement, zinc status (plasma/serum zinc concentration), and the different domains of cognitive functions in school-aged children.

Keywords: Zinc; DNA Synthesis; Plasma

References

1. Nissensohn M., et al. “Effect of Zinc Intake on Mental and Motor Development in Infants: A Meta-Analysis”. International Journal for Vitamin and Nutrition Research 83 (2013): 203-215.
2. Bhatnagar S and Taneja S. “Zinc and cognitive development”. British Journal of Nutrition 85 (2001): 139- 145.
3. Warthon-Medina M., et al. “Zinc intake status and indices of cognitive function in adults and children: a systematic review and meta-analysis”. European Journal of Clinical Nutrition 69 (2015): 649-661.
4. Abdullah Md., et al. “The role of iron and zinc in cognitive development of children”. Asian Journal of Medical and Biological Research 3 (2017): 145-151.
5. Black MM. “The Evidence Linking Zinc Deficiency with Children’s Cognitive and Motor Functioning”. Journal of Nutrition 133 (2003): 1473-1476.
6. Black MM. “Zinc deficiency and child development”. The American Journal of Clinical Nutrition 68 (1998): 464-469.
7. Umamaheswari K., et al. “Effect of iron and zinc deficiency on short term memory in children”. Indian Pediatrics 48 (2001): 289-293.
8. Shashi A., et al. “Linkages of biomarkers of zinc with cognitive performance and taste acuity in adolescent girls”. International Journal of Food Sciences and Nutrition 65 (2014): 399-403.
9. Amani R., et al. “Association of cognitive function with nutritional zinc status in adolescent female students”. Progress in Nutrition 21 (2019): 86-93.
10. , et al. “Zinc Supplementation Improved Cognitive Performance and Taste Acuity in Indian Adolescent Girls”. Journal of the American College of Nutrition 28 (2009): 388-396.
11. Gibson RS., et al. “A growth-limiting, mild zinc-deficiency syndrome in some Southern Ontario boys with low height percentiles”. The American Journal of Clinical Nutrition 49 (1989): 1266-1273.
12. Khodashenas E., et al. “The Effect of Zinc Supplementation on Cognitive Performance in Schoolchildren”. International Journal of Pediatrics 3 (2015): 1033-1038.
13. Asih SR., et al. “Effects of zinc supplementation on nutritional status and cognition”. Paediatrica Indonesiana 46 (2006): 64-70.
14. Pongcharoen T., et al. “Long-term effects of iron and zinc supplementation during infancy on cognitive function at 9 y of age in northeast Thai children: a follow-up study”. The American Journal of Clinical Nutrition 93 (2011): 636-643.
15. Caulfield LE., et al. “Maternal gestational zinc supplementation does not influence multiple aspects of child development at 54 mo of age in Peru”. The American Journal of Clinical Nutrition 92 (2010): 130-136.
16. Christian P., et al. “Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal”. JAMA 304 (2010): 2716-2723.
17. Tamura T., et al. “Effect of zinc supplementation of pregnant women on the mental and psychomotor development of their children at 5 y of age”. The American Journal of Clinical Nutrition 77 (2003): 1512-1516.

Citation

Citation: Gomaa F Salma. “Zinc Deficiency and Association with Cognitive Performance in School-aged Children: Peer Review”.Acta Scientific Medical Sciences 5.11 (2021): .

Copyright

Copyright: © 2021 Gomaa F Salma. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.