Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 5 Issue 10

Cystic Fibrosis in Female Gender

Tiziana Ciarambino1, Ombretta Para2 and Mauro Giordano MD PhD3*

1Dirigente Medico, Ospedale Clinicizzato Marcianise, ASL Caserta, Italy
2Dirigente Medico, Ospedale Careggi, University of Firenze, Italy
3Department of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli“, Naples, Italy

*Corresponding Author: Mauro Giordano MD PhD, Department of Advanced Medical and Surgical Sciences, University of Campania “L. Vanvitelli“, Naples, Italy

Received: July 20, 2021; Published: September 08, 2021


Introduction: Cystic fibrosis (CF) is a lethal autosomal recessive disease. It has been reported that females are diagnosed later than males (2) and have a significantly decreased survival.

Methods: Clinical trials were identified by PubMed until June 30 2020. The search keywords were "sex, gender differences, cystic fibrosis”.

Result: It has been suggested, that cystic fibrosis is diagnosed later in female children, because underdiagnosed. Unfortunately, cystic fibrosis determines airway inflammation and chronic respiratory infection, such as Pseudomonas aeruginosa. Different factors are related to these inflammations. However, mortality and cystic fibrosis–related diabetes (CFRD) prevalence were higher, in female subjects than males.

Conclusion: Female subjects have significantly higher mortality than males, with about 4-year difference in median survival. However, adolescent girls with CF have a greater emotional impact compared to boy.

Keywords: Sex; Gender Differences; Cystic Fibrosis


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Citation: Mauro Giordano., et al. “Cystic Fibrosis in Female Gender”.Acta Scientific Medical Sciences 5.10 (2021): 31-33.


Copyright: © 2021 Mauro Giordano., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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