Acta Scientific Medical Sciences (ISSN: 2582-0931)

Research Article Volume 5 Issue 9

Fetomaternal Outcome in Pregnancy with COVID-19

Shruthi R1, Niruby Rasendrakumar2, Subashini S3 and Nidhi Sharma4*

1MBBS Student, Saveetha Medical College SIMATS, Kuthambaakam, Chennai, Tamil Nadu, India
2Junior Resident, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences , Chennai
3MSc Clinical Embryology, ARC, Saveetha Medical College SIMATS, Kuthambaakam, Chennai, Tamil Nadu, India
4Department of Obstetrics and Gynecology, Saveetha Medical College SIMATS, Kuthambaakam, Chennai, Tamil Nadu, India

*Corresponding Author: Nidhi Sharma, Department of Obstetrics and Gynecology, Saveetha Medical College SIMATS, Kuthambaakam, Chennai, Tamil Nadu, India.

Received: June 26, 2021; Published: August 18, 2021

Citation: Nidhi Sharma., et al. “Fetomaternal Outcome in Pregnancy with COVID-19". Acta Scientific Microbiology 5.9 (2021): 89-94.

Abstract

Aims and Objectives: This study was to done to find the feto-maternal outcome when universal screening for COVID -19 was done in pregnancy. The effects of COVID-19 on placental histology and any evidence of vertical transplacental transmission were also investigated.

Materials and Methods: A total of 850 pregnant women were screened from April 2020-July 2020 Eighty nine mothers were found positive for covid-19 with RTPCR. All pregnancies with covid 19 positive screen were admitted. 30 women were referred to labour room for intrapartum care and their feto maternal outcome was studied.

Results: Covid -19 pregnancy is associated with miscarriages, preterm labour and intrauterine deaths. Placental lesions commonly observed are perivillous fibinous exudates, microthrombi and microinfracts. All newborns were covid negative tested by RT-PCR and hence transplacental transfer is not recorded in this preliminary report.

Conclusion: The placenta acts as a barrier against transmission of COVID -19, though placental affection with microthrombi, infarcts and perivillous fibrosis were evident in almost all placenta in Pregnancy with Covid -19.

Keywords: Covid-19; Pregnancy; Fetus; Newborn; Placenta

Bibliography

  1. WHO. Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV) (2005).
  2. Kwon JY., et al. “New insights into the relationship between viral infection and pregnancy complications”. American Journal of Reproductive Immunology 5 (2014): 387-390.
  3. Brosnihan KB., et al. “Enhanced expression of Ang- (1-7) during pregnancy”. Brazilian Journal of Medical and Biological Research 8 (2004): 1255-1262.
  4. Jamieson DJ., et al. “What obstetrician-gynecologists should know about Ebola: a perspective from the Centers for Disease Control and Prevention”. Obstetrics and Gynecology5 (2014): 1005-1010.
  5. Fisk NM and Atun R. “Systematic analysis of research underfunding in maternal and perinatal health”. BJOG 3 (2009): 347-356.
  6. Hui DS. “Epidemic and emerging coronaviruses (severe acute respiratory syndrome and Middle East respiratory syndrome)”. Clinics in Chest Medicine 1 (2017): 71-86.
  7. Song Z., et al. “From SARS to MERS, thrusting coronaviruses into the spotlight”. Viruses 1 (2019): 59.
  8. Cui J., et al. “Origin and evolution of pathogenic coronaviruses”. Nature Reviews Microbiology (2019).
  9. Zhou Y., et al. “Prospects for a MERS-CoV spike vaccine”. Expert Review on Vaccines8 (2018): 677-686
  10. Su S., et al. “Epidemiology, genetic recombination, and pathogenesis of coronaviruses”. Trends in Microbiology 6 (2016): 490-502.
  11. Lu R., et al. “Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding”. Lancet 10224 (2020): 565-574.
  12. Huang C., et al. “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China”. Lancet 10223 (2020): 497-506.

Copyright: © 2021 Nidhi Sharma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Contact US