Bitarka Bisai and Sirisha L Vavilala*

School of Biological Sciences, University of Mumbai, Kalina Campus, Mumbai, India

*Corresponding Author: Sirisha L Vavilala, Assistant Professor, School of Biological Sciences, University of Mumbai, Kalina Campus, Mumbai, India.

Received: June 28, 2021; Published: July 31, 2021

Citation: Bitarka Bisai and Sirisha L Vavilala. “Neuroprotective Potential of Bioactive Sulfated Polysaccharides from Algae". Acta Scientific Microbiology 5.8 (2021): 169-182.

Abstract

Neurodegenerative diseases are disorders of the central nervous system and common cause of physiological and economic burden worldwide. Most of the current drugs for treatment of Parkinson’s Disease and Alzimer’s Disease aren’t sufficiently effective in preventing their progress and have multiple adverse side-effects. Hence, there is a need for therapeutics from natural sources. Interest for the use and exploitation of the marine algae is expanding. The marine environment is well known for its rich sources of chemical compounds with numerous beneficial health effects. It is known that many marine algae species contain Sulfated Polysaccharides (SPs) and their lower molecular weight oligosaccharide derivatives which are biocompatible, biodegradable and have been shown to offer numerous health benefits. This review highlights the different types of SPs from different algae, their structures, their bioactive potential particularly their immense potential for prevention of neurodegenerative diseases and provide a scientific basis to the development of new generation of phytopharmaceuticals which can be used alone or in combination with other drugs.

Keywords: Neurodegenerative Diseases; Natural Products; Sulfated Polysaccharides; Algae; Antioxidant Potential; Neuroprotective Agent

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Copyright: © 2021 Bitarka Bisai and Sirisha L Vavilala. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.