Mamasaidov AT*, Salieva RSH, Azhimamatova RM and Musaeva BS

Osh State University, Osh, Kyrgyzstan

*Corresponding Author: Mamasaidov AT, Osh State University, Osh, Kyrgyzstan.

Received: June 13, 2021; Published: July 19, 2021

Citation: Mamasaidov AT., et al. “Bronchiolitis in Rheumatoid Arthritis". Acta Scientific Microbiology 5.8 (2021): 69-73.

Abstract

Aim of the Study: This study aimed to evaluate the incidence of bronchiolitis in patients with rheumatoid arthritis (RA) and identify common risk factors and most clinical presentations of rheumatoid bronchiolitis.

Materials and Methodology: In this study, enrolled 156 patients with a confirmed diagnosis of RA. All studied patients underwent chest computed tomography (CT) scan conventional clinic and functional examination of the respiratory system and methods of detection of risk factors.

Results: According to the CT report signs of bronchiolitis were found in 46 (29,5%) of patients with bronchiolitis. Clinical symptoms of bronchiolitis found just in 24 (52,2%) of cases patients with CT scan signs of bronchiolitis. Rheumatoid bronchiolitis associated with smocking, male sex, early age debuted RA, and high level of DAS 28, rheumatoid factor (RF), Anti-cyclic citrullinated peptide antibody (ACCP), and spontaneous B lymphocyte activation.

Conclusion: Bronchiolitis (based on CT scan report) is a frequent extra-articular symptom of RA, and it is a common type of pathology of the respiratory system in this disease and is observed in almost 30% of patients with RA. The clinical presentation of the identified only 50% cases of radiologically confirmed signs of bronchiolitis and other remaining 50% case a subclinical (less symptomatic) variant of rheumatoid bronchiolitis is determined. The estimated risk factors of rheumatoid bronchiolitis are cigarette smoking, male gender, early debuted RA, and high level of DAS28, RF, ACCP and SBL.

Keywords: Rheumatoid Arthritis; Bronchiolitis; Computed Tomography; Clinical Signs of Bronchiolitis; Risk Factors of Bronchiolitis

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Copyright: © 2021 Mamasaidov AT., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.