Acta Scientific Medical Sciences (ISSN: 2582-0931)

Research Article Volume 5 Issue 8

Bronchiolitis in Rheumatoid Arthritis

Mamasaidov AT*, Salieva RSH, Azhimamatova RM and Musaeva BS

Osh State University, Osh, Kyrgyzstan

*Corresponding Author: Mamasaidov AT, Osh State University, Osh, Kyrgyzstan.

Received: June 13, 2021; Published: July 19, 2021

Citation: Mamasaidov AT., et al. “Bronchiolitis in Rheumatoid Arthritis". Acta Scientific Microbiology 5.8 (2021): 69-73.

Abstract

Aim of the Study: This study aimed to evaluate the incidence of bronchiolitis in patients with rheumatoid arthritis (RA) and identify common risk factors and most clinical presentations of rheumatoid bronchiolitis.

Materials and Methodology: In this study, enrolled 156 patients with a confirmed diagnosis of RA. All studied patients underwent chest computed tomography (CT) scan conventional clinic and functional examination of the respiratory system and methods of detection of risk factors.

Results: According to the CT report signs of bronchiolitis were found in 46 (29,5%) of patients with bronchiolitis. Clinical symptoms of bronchiolitis found just in 24 (52,2%) of cases patients with CT scan signs of bronchiolitis. Rheumatoid bronchiolitis associated with smocking, male sex, early age debuted RA, and high level of DAS 28, rheumatoid factor (RF), Anti-cyclic citrullinated peptide antibody (ACCP), and spontaneous B lymphocyte activation.

Conclusion: Bronchiolitis (based on CT scan report) is a frequent extra-articular symptom of RA, and it is a common type of pathology of the respiratory system in this disease and is observed in almost 30% of patients with RA. The clinical presentation of the identified only 50% cases of radiologically confirmed signs of bronchiolitis and other remaining 50% case a subclinical (less symptomatic) variant of rheumatoid bronchiolitis is determined. The estimated risk factors of rheumatoid bronchiolitis are cigarette smoking, male gender, early debuted RA, and high level of DAS28, RF, ACCP and SBL.

Keywords: Rheumatoid Arthritis; Bronchiolitis; Computed Tomography; Clinical Signs of Bronchiolitis; Risk Factors of Bronchiolitis

Bibliography

  1. Turesson C. “Extra-articular rheumatoid arthritis”. Current Opinion on Rheumatology 3 (2013): 360-366.
  2. Nesterovich II., et al. “Complex clinical and nstrumental evaluation of lung injury in patients with rheumatoid arthritis”. Nauchno-Prakticheskaya Revmatologiya = Rheumatology Science and Practice 5 (2006): 535-542.
  3. Olson AL., et al. “Rheumatoid arthritis – interstitial lung disease-associated mortality”. American Journal of Respiratory and Critical Care Medicine 3 (2011): 372-378.
  4. Lahdensuo A., et al. “Bronchiolitis in rheumatoid arthritis”. Chest 85 (1984): 705-798.
  5. Schwarz MI., et al. “Bronchiolitis obliterans: the lone manifestation of rheumatoid arthritis”. European Respiratory Journal 7 (1994): 817-820.
  6. Sheyanov MV., et al. “Lesions of the distal bronchi in patients with rheumatoid arthritis”. Scientific - Practical Rheumatology 6 (2009): 14-19.
  7. Mori S., et al. “Small airway obstruction in patients with rheumatoid arthritis”. Modern Rheumatology 2 (2013): 164-173.
  8. Avnon LS., et al. “Pulmonary functions testing in patients with rheumatoid arthritis”. Israel Medical Association Journal (IMAJ) 2 (2009): 83-87.
  9. Mamasaidov AT., et al. “Spontaneous antigen-specific B-cell activity in early rheumatoid arthritis and reactive arthritis”. Scientific and practical rheumatology (Moscow) 51 (2013):
  10. Mamasaidov AT., et al. “The incidence and nature of the pathology of the respiratory system in rheumatoid arthritis”. Central Asian Medical Journal 19 (2013): 59.
  11. Aubart F., et al. “High levels of anti-cyclic citrullinated peptide autoantibodies are associated with co-occurrence of pulmonary diseases with rheumatoid arthritis”. Journal of Rheumatology 6 (2011): 979–982.
  12. Mamasaidov AT., et al. “Indicators of spontaneous proliferation of B-lymphocytes in the diagnosis of neurological manifestations of rheumatoid arthritis”. Journal of Neurology and Psychiatry9 (2009): 63-66.
  13. Brown KK. “Rheumatoid lung disease”. Proceedings of the American Thoracic Society 4 (2007): 443-448.
  14. Homma S., et al. “Diffuse panbronchiolitis in rheumatoid arthritis”. European Respiratory Journal 12 (1998): 444-452.
  15. Ternovoy SK., et al. “Multislice computed tomography in the diagnosis of lung lesions in patients with rheumatoid arthritis”. Meditsinskaya Vizualizatsiya 5 (2009): 33-38.
  16. Perez-Darame R., et al. “Rheumatoid arthritis-associated interstitial lung disease: lung inflammation evaluated with high resolution computed tomography scan is correlated to rheumatoid arthritis disease activity”. Reumatology Clinic 11 (2015): 12-16.
  17. Habib HM., et al. “Pulmonary involvement in early rheumatoid arthritis patients”. Clinical Rheumatology 2 (2011): 217-221.
  18. Assayag D., et al. “Predictors of mortality in rheumatoid arthritis- related interstitial lung disease”. Respirology 4 (2014): 493-500.
  19. Kelly CA., et al. “Rheumatoid arthritis-related interstitial lung disease: associations, prognostic factors and physiological and radiological characteristics – a large multicenter UK study. Rheumatology (Oxford) 9 (2014): 1676-1682.
  20. Gochuico BR., et al. “Progressive preclinical interstitial lung disease in rheumatoid arthritis”. Archives of Internal Medicine 2 (2008): 159-166.
  21. Bestaev DV., et al. “Comparative clinical, laboratory, and instrumental evaluation of interstitial lung changes in rheumatoid arthritis”. Nauchno-Prakticheskaya Revmatologiya = Rheumatology Science and Practice 3 (2014): 277-282.
  22. Yin Y., et al. “Anti-cyclic citrullinated рeptide antibody is associated with interstitial lung disease in patients with rheumatoid arthritis. PLoS One 4 (2014): e92449.

Copyright: © 2021 Mamasaidov AT., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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