Acta Scientific Medical Sciences (ISSN: 2582-0931)

Case ReportVolume 5 Issue 6

Vulvar Lichen Simplex Chronicus: From Diagnosis to Treatment

Chernova NI1 and Zadorozhnaya IS2*

1Department of Healthcare, Moscow Research and Practical Center for Dermatovenerology and Cosmetology, Moscow, Russian Federation
2Moscow State Medical and Dental University Named After A.I. Evdokimova, Moscow, Russian Federation

*Corresponding Author: Zadorozhnaya IS, Moscow State Medical and Dental University Named After A.I. Evdokimova, Moscow, Russian Federation.

Received: March 02, 2021; Published: May 22, 2021

Citation: Chernova NI and Zadorozhnaya IS. “Vulvar Lichen Simplex Chronicus: From Diagnosis to Treatment". Acta Scientific Microbiology 5.6 (2021): 121-124.

Abstract

  Lichen simplex chronicus (LSC) of the vulva is a chronic pruritic dermatosis with unknown etiology, prone to recurrence and significantly affecting the quality of life of patients. Despite the rather typical clinical picture in the form of lichenized papules and plaques, the diagnosis can be difficult and take a period from several months to several years from the moment of the patient's first visit to a dermatovenerologist or gynecologist. The latter contributes to the chronicity of the pathological process, creates difficulties in treatment, and can lead to sexual and psychoemotional disorders in patients up to suicidal thoughts. In this case, we present a 32-year-old female patient with a diagnosis of vulvar LSC, who was followed up with an erroneous diagnosis of vulvar scleroderma for five years, receiving ineffective treatment, which led to neurotic disorders and sexual dysfunction. After establishing the correct diagnosis and conducting therapy according to the European guidelines for the management of patients with LSC in the anogenital area with additional local application of platelet autoplasma, a stable remission of dermatosis and an improvement in the patient's quality of life were achieved.

Keywords: Lichen Simplex Chronicus; Treatment; Platelet-rich Plasma

Bibliography

  1. Rajalakshmi R., et al. "Lichen simplex chronicus of anogenital region: а clinico-etiological study". Indian Journal of Dermatology, Venereology, and Leprology 1 (2011): 28-36.
  2. Ikoma Akihiko., et al. "The neurobiology of itch”. Nature Reviews Neuroscience7 (2006): 535-547.
  3. Van der Meijden Willem I., et al. "2016 European guideline for the management of vulval conditions”. Journal of the European Academy of Dermatology and Venereology6 (2017): 925-941.
  4. Chernova NI., et al. "Possibilities of enhancing the efficiency of therapy in patients with the most common vulvar diseases". Russian Bulletin of Obstetrician-Gynecologist4 (2016).
  5. Alves Rubina and Ramon Grimalt. "A review of platelet-rich plasma: history, biology, mechanism of action, and classification”. Skin Appendage Disorders1 (2018): 18-24.
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  8. Tedesco Marinella., et al. "Adipose tissue stromal vascular fraction and adipose tissue stromal vascular fraction plus platelet‐rich plasma grafting: New regenerative perspectives in genital lichen sclerosus”. Dermatologic Therapy (2020): e14277.

Copyright: © 2021 Chernova NI and Zadorozhnaya IS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



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