Abstract

Plants have been used as a source of food material and natural remedies for the treatment of various ailments. Medicinal plants exhibit various pharmacological activities due to the presence of one or more phytoconstituents such as alkaloids, glycosides, flavonoids, terpenes etc. Coumarins (1, 2 benzopyrones) are a large group of naturally occurring secondary metabolites present in higher plants. Esculetin (6, 7-dihydroxycoumarin) is a coumarin derivative found in a plant, Cichorium intybus which is widely distributed in Europe and other parts of the world. It is also present in a Chinese plant, Bougainllra spectabillis and used as folk medicines. Although it is found in herbal medicines, exhibit various pharmacological actions such as antioxidant, hepatoprotective, anti-inflammatory, anticancer, hypoglycemic and chemopreventive action. Only limited scientific research has been published. The aim of this review is to collect all available scientific information which will provide valuable information to researchers in further development and screening methods for the treatment of various diseases by using esculetin as a potential molecule.

Keywords: Esculetin; Anti-inflammatory; Coumarins; Proliferative; Alkaloids; Saponinis

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Citation

Citation: Manoj Gadewar., et al. “Pharmacological and Analytical Aspects of Esculetin: A Comprehensive Review”.Acta Scientific Medical Sciences 5.2 (2021): 105-110.

Copyright

Copyright: © 2021 Manoj Gadewar., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.