Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Case Report Volume 5 Issue 1

Posterior Reversible Encephalopathy Syndrome in Primigravida with Severe Pre-eclampsia and Hellp

Sevim Özden1*, Christina Lindegaard Poulsen2 and Mohammed R Khalil2

1Department of Anesthesiology, Sygehus Lillebaelt, Kolding, Denmark
2Department of Obstetrics and Gynaecology, Sygehus Lillebaelt, Kolding, Denmark

*Corresponding Author: Sevim Özden, Department of Anesthesiology, Sygehus Lillebaelt, Kolding, Denmark.

Received: October 22, 2020; Published: December 08, 2020



  Posterior reversible encephalopathy syndrome (PRES) is a neuroradiologic condition characterized by a range of symptoms such as headache, nausea, vomiting, blurred vision, altered consciousness, seizures, and focal neurological symptoms. It can be associated with HELLP syndrome. In this case report, we present 29 years old primigravida at 36+6 weeks’ gestation with HELLP syndrome and severe preeclampsia with loss of vision on both eyes. The patient was further examined with a CT brain scan, which initially indicated that she had posterior reversible encephalopathy syndrome (PRES). Neuro radiologist provided a second interpretation of the CT brain scan with no sign of PRES. However, the clinical presentation indicated signs of PRES and the patient got treatment with antihypertensive and Magnesium Sulphate at the intensive care unit and had uneventful caesarean section performed. This case report emphasizes the importance of early recognition, correct treatment, and management to prevent further complications.

Keywords: Hypertension; Pre-eklampsia; HELLP; Pregnancy; PRES; Loss of Vision



  1. Lise Hald Nielsen., et al. “Hypertension and preeclampsia”. DSOG guideline (2018).
  2. Seda Ates., et al. “Posterior reversible encephalopathy associated with HELLP syndrome: A case report and review of the literature”. Neurology Asia1 (2015): 91-94.
  3. Screenivasa Rao Sudulagunta., et al. “Posterior reversible encephalopathy syndrome (PRES)”. Oxford Medical Case Reports 4 (2017).
  4. Marlene Fischer and Erich Schmutzhard. “Posterior reversible encephalopathy syndrome”. Journal of Neurology 264 (2017): 1608-1616.
  5. Moulay Abdellah Babahabib., et al. “Posterior reversible encephalopathy syndrome in patient of severe preeclampsia with Hellp syndrome immediate postpartum”. Pain African Medical Journal (2015): 21-60.
  6. Jeniffer E Fugate and Alejandro A Rabinstein. “Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology and outstanding questions”. The Lancet Neurology9 (2015): 914-925.
  7. Terry A Neill. “Reversible posterior leukoencephalopathy syndrome”. UpToDate. Wolters Kluwer.
  8. Anne Albers Aeen. Jørgen Jeppesen. Hayder Obaid. Hans henrik Bülow. Post partum posterior reversibelt encefalopati-syndrom. Ugeskr Læger (2015): 177.
  9. Anand Kumar Verma., et al. “Posterior encephalopathy syndrome in women with eclampsia: Predictors and outcome”. Elsevier 10 (2017): 74-82.
  10. Ilda Amirian., et al. “Posterior reversibel encefalopatisk syndrom hos en gravid”. Ugeskr Læger 180 (2018): V01180049


Citation: Sevim Özden., et al. “Posterior Reversible Encephalopathy Syndrome in Primigravida with Severe Pre-eclampsia and Hellp". Acta Scientific Medical Sciences 5.1 (2021): 14-16.


Acceptance rate30%
Acceptance to publication20-30 days
Impact Factor1.403

Indexed In

News and Events

  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is May 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US