Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 4 Issue 9

Synthesis of Some Oxazine Compounds Derived from TDI and Schiff Bases

Ghufran T Sadeek, Mohammad S Al-Ajely* and Neam H Saleem

Chemistry Department, College of Education for Girls, College of Education for Pure Science, Mosul, Iraq

*Corresponding Author: Mohamed S AL-Ajely, Chemistry Department, College of Education for Girls, College of Education for Pure Science, Mosul, Iraq.

Received: August 05, 2020; Published: August 31, 2020

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Abstract

  It is known from ongoing research on heterocyclic compounds that these compounds are used as drug and drug carriers, According to FDI reports that these compounds forms 90% drug for cancer and 75% drugs for different diseases. It was also known from our studies on oxazine compounds that this type of heterocyclic compounds had versatile application in medicine. In this study, new 3,1-Benzoxazine compounds (S7-12) were prepared by cyclization reaction of some 2-(benzylidene-amino) benzoic acids (S1-6) with 2, 4- diisocyano1-methylbenzene (TDI) under reflex conditions in chloroform. The structure of the synthesized compounds were confirmed by IR, 1HNMR spectral studies.

Keywords: Oxazine Compounds; Insects; Fungi; 1HNMR

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Citation

Citation: Mohamed S AL-Ajely., et al. “Synthesis of Some Oxazine Compounds Derived from TDI and Schiff Bases". Acta Scientific Medical Sciences 4.9 (2020): 120-128.




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