Himanshu Rohela1*, Sameer Tulpule2, Nevitha Athikhari3, Deepthi Murthy4 and Raj H Vhatkar1
1Department of Orthopaedic Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India
2Department of Haematooncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India
3Department of Histopathology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India
4 Department of Histopathology, Dr Lal Path Paths, National Reference Laboratory, Delhi, India
*Corresponding Author: Himanshu Rohela, Department of Orthopaedic Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India.
Received: May 20, 2020; Published: July 28, 2020
Lymphoplasmacytic lymphoma (LPL) is a low-grade, B-cell neoplasm composed of small lymphocytes, plasmacytoid lymphocytes, and plasma cells that typically involve the bone marrow, and it is associated with an immunoglobulin M (IgM) gammopathy. The diagnosis of LPL itself can be challenging because LPL lacks disease-specific morphologic, immunophenotypic, and genetic features to differentiate it from other mature B-cell neoplasms. Although most cases of LPL are IgM secreting, there are exceptions of rare, primary, lymph node-based presentations of LPL or lymphoplasmacytic B-cell proliferations in the bone marrow associated with IgA or IgG gammopathies. We hereby report a case of IgG secreting lymphoplasmacytic lymphoma under our tracking and review of the related literature on management of this rare tumor.
Keywords: Waldenstrom Macroglobulinemia (WL); Lymphoplasmacytic Lymphoma (LPL)
Citation: Himanshu Rohela., et al. “Non Waldenstrom Macroglobulenemia Igg Secreting Lymphoplasmacytic Lymphoma - A Diagnostic Challenge". Acta Scientific Medical Sciences 4.8 (2020): 107-110.
Copyright: © 2020 Himanshu Rohela., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.