Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 4 Issue 8

Comparison of Propofol and Fentanyl in Prevention of Emergence of Delirium after Sevoflurane Anesthesia

Hiren R Patel1* and Geeta Parikh2

1Kasturba Vaidyakiya Rahat Mandal, Gujarat, India
2Department of Anaesthesiology and Critical Care, Institute of Kidney Disease and Research Center, and Institute of Transplant Sciences, Civil Hospital Campus, Ahmedabad, India

*Corresponding Author: Hiren R Patel, Kasturba Vaidyakiya Rahat Mandal, Gujarat, India.

Received: July 09, 2020; Published: July 20, 2020



Introduction: The occurrence of emergence agitation in children after sevoflurane anaesthesia is common with an incidence ranging between 10 to 80%.

Aim: To study Propofol and Fentanyl in Prevention of Emergence of Delirium after Sevoflurane Anesthesia.

Material and Methods: After approval from ethical committee and written informed consent from parents or guardian, 115 children with ASAI and II aged 2 to 6 years, were selected for elective urological surgery, under sevoflurane anaesthesia. Patients were divided into three groups i.e. Group C (Control), Group F (Fentanyl), and Group P (Propofol). All collected data enter into the IBM SPSS 20th (statistical parameter of soci 20th and analyzed it. Continuous data expressed as mean ± sd and non-continuous expressed as in percentages. Anova test, kruskal wallis and chi square (fisher exact) test have been performed to carry out p value at 95% CI. p value <0.05 shows statistically significant.

Result: In score 1, child is obtunded with no response to stimulation, in stage 2, child is asleep but responsive to movement or stimulation, in stage 3, child is awake and responsive while score 4 includes crying and in score 5 thrashing behavior that requires restraint. We found highest score in group S that is around 4 compared to group F and group P. The control group children were awake and responsive but most of the children were crying from five minutes onwards and some children had thrashing behavior. Amongst group F and group P, group P is better than group f. Group P children were more sedated compared to group F. After 30 minutes, almost all children were awake and responsive. This emergence of Agitation at 5 min, 10 min, 15 min was significantly higher in Control and Propofol group as compared to Fentanyl and Control (P < 0.01 respectively).

Conclusion: We concluded that fentanyl and propofol both have effect on reduction of emergence agitation after sevoflurane anaesthesia but the children of propofol group remains calm and quiet and have significant reduction in emergence delirium than fentanyl at 10 and 15 mins after discontinuation of sevoflurane anaesthesia.

Keywords: Propofol; Fentanyl; Sevoflurane; Emergence of Delirium



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Citation: Hiren R Patel and Geeta Parikh. “Comparison of Propofol and Fentanyl in Prevention of Emergence of Delirium after Sevoflurane Anesthesia". Acta Scientific Medical Sciences 4.8 (2020): .


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