Acta Scientific Medical Sciences (ASMS)(ISSN: 2582-0931)

Research Article Volume 4 Issue 8

Echocardiographic Assessment at 1-Year Follow-Up Post-Percutaneous Pulmonary Valve Implantation at the Prince Sultan Cardiac Center: A Single-Center Experience

Al Asmari Own*, Atiyah Merna, Al Essa Mohammed, Almohaizy Omar, Al Sahari Atif, Mohsin Shazia, Al Khalaf Khalaf and Al Najashi Khalid

Department of Pediatric Cardiology, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia

*Corresponding Author: Al Asmari Own, Department of Pediatric Cardiology, Prince Sultan Cardiac Center, Riyadh, Kingdom of Saudi Arabia.

Received: July 04, 2020; Published: July 18, 2020

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Abstract

Background: Congenital heart defects affect roughly 1 in 150 people and are often associated with right ventricular outflow tract (RVOT) dysfunction. The aim of the study was to evaluate the echocardiographic changes within the right ventricle following percutaneous pulmonary valve implantation (PPVI).

Methods: The echocardiographic data of 57 patients who had pulmonary valve stenosis and/or regurgitation and had undergone PPVI treatment and completed at least 1 year of regular follow-up at the Prince Sultan Cardiac Center from January 2012 to December 2015 were analyzed at the baseline level (before PPVI) and at 6 and 12 months following the PPVI treatment. Pulmonary insufficiency was graded from 0 to 4 based on severity: 0, none; 1, trivial; 2, mild; 3, moderate; 4, severe/free).

Results: There was a significant reduction in the RVOT gradient. At baseline, 95% of the subjects demonstrated pulmonary insufficiency (grades 2-4); at 12 months, 28% had decreased pulmonary insufficiency and 72% had limited to no pulmonary regurgitation. Other parameters, including right ventricular volumes, fractional area change, and the tricuspid regurgitant jet width/body surface area, did not demonstrate any significant change. Early follow-up echocardiographic data demonstrated persistent improvement in the RVOT gradient and pulmonary regurgitation level over the 1-year follow-up.

Conclusion: PPVI was seen to ameliorate RVOT dysfunction in most subjects.

Keywords: Congenital Heart Defects; Right Ventricular Outflow Tract; Percutaneous Valve Implantation; Echocardiography

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References

  1. Biernacka EK., et al. “Percutaneous pulmonary valve implantation - state of the art and Polish experience”. Postepy Kardiol Interwencyjnej 13 (2017): 3-9.
  2. Conte S., et al. “Homograft valve insertion for pulmonary regurgitation late after valveless repair of right ventricular outflow tract obstruction”. European Journal of Cardio-Thoracic Surgery 15 (1999): 143-149.
  3. Perron J., et al. “Valved homograft conduit repair of the right heart in early infancy”. The Annals of Thoracic Surgery 68 (1999): 542-548.
  4. Bando K., et al. “Outcome of pulmonary and aortic homografts for right ventricular outflow tract reconstruction”. The Journal of Thoracic and Cardiovascular Surgery 109 (1995): 509-517.
  5. Homann M., et al. “Reconstruction of the RVOT with valved biological conduits: 25 years experience with allografts and xenografts”. European Journal of Cardio-Thoracic Surgery 17 (2000): 624-630.
  6. Dearani JA., et al. “Late follow-up of 1095 patients undergoing operation for complex congenital heart disease utilizing pulmonary ventricle to pulmonary artery conduits”. The Annals of Thoracic Surgery 75 (2003): 399-411.
  7. Boethig D., et al. “Evaluation of 188 consecutive homografts implanted in pulmonary position after 20 years”. European Journal of Cardio-Thoracic Surgery 32 (2007): 133-142.
  8. Stark J., et al. “Fate of subpulmonary homograft conduits: determinants of late homograft failure”. The Journal of Thoracic and Cardiovascular Surgery 115 (1998): 506-514.
  9. Oosterhof T., et al. “Long-term follow-up of homograft function after pulmonary valve replacement in patients with tetralogy of Fallot”. European Heart Journal 27 (2006): 1478-1484.
  10. Shebani SO., et al. “Right ventricular outflow tract reconstruction using Contegra valved conduit: natural history and conduit performance under pressure”. European Journal of Cardio-Thoracic Surgery 29(2006):397-405.
  11. Kanter KR., et al. “One hundred pulmonary valve replacements in children after relief of right ventricular outflow tract obstruction”. The Annals of Thoracic Surgery 73 (2002): 1801-1806.
  12. Bouzas B., et al. “Pulmonary regurgitation: not a benign lesion”. European Heart Journal 26 (2005): 433-439.
  13. Karamlou T., et al. “Surgery insight: late complications following repair of tetralogy of Fallot and related surgical strategies for management”. Nature Clinical Practice Cardiovascular Medicine 3 (2006): 611-622.
  14. Cesnjevar R., et al. “Late pulmonary valve replacement after correction of Fallot’s tetralogy”. Thoracic and Cardiovascular Surgery 52 (2004): 23-28.
  15. Bielefeld MR., et al. “Reoperative homograft right ventricular outflow tract reconstruction”. The Annals of Thoracic Surgery 71 (2001): 482-487.
  16. Bonhoeffer P., et al. “Percutaneous replacement of pulmonary valve in a right-ventricle to pulmonary-artery prosthetic conduit with valve dysfunction”. Lancet 356 (2000): 1403-1405.
  17. Lurz P., et al. “Percutaneous pulmonary valve implantation: impact of evolving technology and learning curve on clinical outcome”. Circulation 117 (2008): 1964-1972.
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Citation

Citation: Al Asmari Own., et al. “Echocardiographic Assessment at 1-Year Follow-Up Post-Percutaneous Pulmonary Valve Implantation at the Prince Sultan Cardiac Center: A Single-Center Experience". Acta Scientific Medical Sciences 4.8 (2020): 46-50.



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