Acta Scientific Medical Sciences (ISSN: 2582-0931)

Short Communication Volume 4 Issue 4

Bioactive Compounds and Anti-Microbial Activity of Ventilago denticulata Fruits and its Toxicity to Artemia salina L

Adya Anindita Dash and Sanjeet Kumar*

Biodiversity and Conservation Lab, Ambika Prasad Research Foundation, Odisha, India

*Corresponding Author: Sanjeet Kumar, Biodiversity and Conservation Lab, Ambika Prasad Research Foundation, Odisha, India.

Received: March 02, 2020; Published: March 19, 2020



  Despite number of allopathic medicines, the infectious diseases are burning issues due to Aniti-microbial Resistance (AMR). Therefore, need to screen new source from biowealth. Keeping this in view, an attempt has been made to qualitative analysis of bioactive compounds; evaluate the antibacterial activity against Gram positive bacteria (Streptococcus pyogens) and estimation of toxicity to Artemia salina. The results revealed that fruit extracts rich with phenolic compounds. The MIC (Minimum Inhibitory Concentration) was done using Broth Dilution Assay and it was observed that methanol extract of Ventilago denticulata (Fruits) showed an excellent activity against S. pyogens. It was noted that methanol extract showed 80% inhibition after 24 hrs against brine. The present study highlights the antibacterial potential of common plant of Odisha and recommended to isolate the responsible compound(s) to formulate new drugs to fight against AMR.

Keywords: History; Utilization; Spectacle Correction; Young Adults



  1. Petrovska BB. “Historical review of medicinal plants”. Pharmacognosy Reviews 6.11 (2012): 1-5.
  2. Edeoga HO., et al. “Phytochemical Constituents of some Nigerian Medicinal plants”. African Journal of Biotechnology 4.7 (2005): 685-688.
  3. World Health Organization (WHO). Chronicle 39 (1985): 51-59.
  4. Kumar S., et al. “Ethnobotany and bioactive compounds in leaf of Bixa orellana L. and its toxicity to Artemia salina L”. Plant Science Research 34.1-2 (2012): 93-96.
  5. Farahmandfar R., et al. “Bioactive compounds, antioxidant and antimicrobial activities of Arum maculatum leaves extracts as affected by various solvents and extraction methods”. Food Science and Nutrition (2019).
  6. Preeti M., et al. “In Vitro Anthelminthic activities of whole plant of Ventilago denticulata Wild. Against Pheretima postuma”. Asian Journal of Pharmaceutical and Clinical Research 5.3 (2012): 200-201.
  7. Havsteen B. “Flavonoids, a class of natural products of high pharmacological potency”. Biochemical Pharmacology 32 (1983):1141-1148.
  8. Harbone JB. Phytochemical methods. Chapman and Hall, Ltd”. London (1973).
  9. Meyer BN., et al. “Brine shrimp: A convenient general bioassay for active plant constituents”. Planta Medica 45 (1982): 31-34.
  10. Krishnaraju AV., et al. “Assessment of bioactivity of Indian Medicinal plants using brine shrimp lethality assay”. International Journal of Applied Science and Engineering 3.2 (2005): 125-134.
  11. McLaughlin JL., et al. “Simple Bench-Top Bioassays (Brine Shrimp and Potato Discs) for the Discovery of Plant Antitumor Compounds”. Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette (1991).
  12. Criel GRJ and Macrae HT. “Artemia morphology and structure. Biology of Aquatic Organisms. Kluwer academic Publishers”. The Netherlands (2002).
  13. Nayak S., et al. “Design and synthesis of (E)-4-(2H-Chromen-3-yl) but-3-en-2-ones and evaluation of their In vitro antimicrobial activity”. Letters in organic Chemistry 12 (2015): 1-7.
  14. Paudel B., et al. “Estimation of antioxidant, antimicrobial activity and brine shrimp toxicity of plants collected from Oymyakon region of the Republic of Sakha (Yakutia), Russia”. Biological Research 47.1 (2014): 1-10.
  15. Pongjanta A., et al. Antioxidant activity and cytotoxic Effect of Ventilago denticulata Wild leaves extracts 1 (2016): 51-57.


Citation: Adya Anindita Dash and Sanjeet Kumar. “Bioactive Compounds and Anti-Microbial Activity of Ventilago denticulata Fruits and its Toxicity to Artemia salina L". Acta Scientific Medical Sciences 4.4 (2020): 93-96.


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