Acta Scientific Medical Sciences (ISSN: 2582-0931)

Literature Review Volume 4 Issue 3

Root Canal Medicaments - Literature Review

Salma A Salama1 and Aya A Salama2*

1Faculty of Dentistry (Medical Sciences-Biochemistry Department)-British University of Egypt
2Lecturer, Department of Fixed Prosthodontics, Faculty of Dentistry, MSA University, Egypt

*Corresponding Author: Aya A Salama, Lecturer, Department of Fixed Prosthodontics, Faculty of Dentistry, MSA University, Egypt. E-mail:

Received: January 18, 2020; Published: February 19, 2020



Objective: Identify, through an integrative literature review, the general update on clinical studies, current research and new developments in the area of root canal pastes, endodontic cements and dressings.

Method: The scientific electronic bases were used: MEDLINE, PUBMED, and COCHRANE for assessing ADM’s class III medical devices: Odontopaste, Odontocem and Odontocide, to determine if these products are in line with recent best dental practice.The research took place between March and December 2019, for articles published between the period 2007 to 2019. Exclusion criteria were: editorials, abstracts, theses and dissertations..

Results: 21 articles were found that reflected relevant aspects of the medical root canal medicaments. .

Conclusion: For a wide range of materials currently available on the market, ADM’s class III medical devices: Odontopaste, Odontocem and Odontocide meet the requirements of a formulation which is compatible with recent restorative and endodontic practice and in regards the active ingredients in all three products no safety complains was reported from any in the last 12 months research.

Keywords: Root Canal Therapy; Endodontics; And Root Canal Obturation



  1. Esra P., et al. “Revascularization: a review of clinical reports on a contemporary treatment modality for endodontics”. Biomedical Research 28.2 (2017): 644-656.
  2. Wilson C., et al. “Clonal diversity in biofilm formation by Enterococcus faecalis in response to environmental stress associated with endodontic irrigants and medicaments”. International Endodontic Journal 48 (2015): 210-219. 
  3. Ramaprabha B and Srilekha J. “Antibiotics in endodontics - A concise review”. International Journal of Applied Dental Sciences 3.4 (2017): 323-329.
  4. Athanassiadis M., et al. “The effect of calcium hydroxide on the steroid component of ledermix and odontopaste”. International Endodontic Journal 44.12 (2011): 1161-1169.
  5. Jarrett J., et al. “Development of techniques for determination of primary components of dental medicament paste mixtures for root canal treatment”. Journal of Investigative and Clinical Dentistry (2017): e12294. 
  6. D’Mello G and Moloney L. “Management of coronal discolouration following a regenerative endodontic procedure in a maxillary incisor”. Australian Dental Journal 62 (2017): 111-116. 
  7. Lenherr P., et al. “Tooth discoloration induced by endodontic materials: a laboratory study”. International Endodontic Journal 45 (2012): 942-949.
  8. Plutzer B., et al. “Comparative efficacy of endodontic medicaments and sodium hypochlorite against Enterococcus faecalis biofilms”. Australian Dental Journal (2017). 
  9. Sood S., et al. “Enterococcal infections and antimicrobial resistance”. Indian Journal of Medical Research 128.2 (2008):111-121.
  10. Segura-Egea J., et al. “Antibiotics in Endodontics: a review”. International Endodontic Journal 50 (2017): 1169-1184.
  11. Diogenes A., et al. “An update on clinical regenerative endodontics”. Endodontic Topics 28 (2013): 22-23.
  12. Kontakiotis EG., et al. “Regenerative endodontic therapy: a data analysis of clinical protocols”. Journal of Endodontics 41(2015): 146-154.
  13. Li Z., et al. “Direct pulp capping with calcium hydroxide or mineral trioxide aggregate: a meta-analysis”. Journal of Endodontics 41 (2015): 1412-1417.
  14. Donaldson M and Goodchild JH. “Is clindamycin dangerous?” General Dentistry 65.4 (2017):12-15.
  15. Sonja A., et al. “Biodentine as a furcal perforation repair material – A case series”. Medicinski Pregled 7.8 (2017): 223-225.
  16. Joana M., et al. “Tooth Discoloration Induced by Different Calcium Silicate–based Cements: A Systematic Review of In-Vitro Studies”. American Association of Endodontists 43.10 (2017): 1593-1601.
  17. Teoh Yu., et al. “Sealing Ability of Alkaline Endodontic Cements versus Resin Cements”. Materials 10.11 (2017): 1-7.
  18. Andrada T., et al. “Antibacterial and antifungal activity of endodontic intracanal medications”. Clujul Medical 90.3 (2017): 344-347. 
  19. Athanassiadis B and Walsh L. “Aspects of Solvent Chemistry for Calcium Hydroxide Medicaments”. Materials 10 (2017): 1219.
  20. Madarati AA., et al. “Preference and usage of intracanal medications during endodontic treatment”. Saudi Medical Journal 38 (2017): 755-763. 
  21. Teoh YY., et al. “The influence of aqueous and PEG 400 solvent vehicles on hydroxyl ion release from calcium hydroxide medicaments”. International Dental Journal 11 (2016): 42-50.
  22. Australian Society of Endodontology (WA) (2017).
  23. Zilm P., et al. “D-amino acids reduce Enterococcus faecalis biofilms in vitro and in the presence of antimicrobials used for root canal treatment”. Plos ONE 12.2 (2017): e0170670. 


Citation: Salma A Salama and Aya A Salama. “Root Canal Medicaments - Literature Review". Acta Scientific Medical Sciences 4.3 (2020): 102-106.


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