Dibyajyoti Banerjee*

Professor and Head, Department of Radiotherapy, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

*Corresponding Author: Dibyajyoti Banerjee, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Received: May 25, 2018; Published: June 01, 2018

Citation: Dibyajyoti Banerjee. “Insulin Plays the Role of a Double-Edged Sword for the Pathogenesis of Tuberculosis in the Context of Diabetes Mellitus”. Acta Scientific Medical Sciences 2.5 (2018).

  More than one-third of the world population is infected with Mycobacterium tuberculosis [1]. Many of them are suffering from diabetes mellitus [2]. In fact, diabetes mellitus is recognized as a potential risk factor for tuberculosis [3]. Prediabetes is an early stage in the course of type 2 diabetes mellitus. It is associated with glucose intolerance and hyperinsulinemia. Recent reports suggest that the pre-diabetes stage is also an independent risk factor for tuberculosis [4-6]. However, in prediabetes, the glycated hemoglobin (HbA1C) is around 5.7 - 6.4% [7], but authorities still believe that HbA1C below 7% is not enough to increase the risk of tuberculosis [8]. Therefore, the increased association of tuberculosis with prediabetes may be caused by some factors other than the glycation state (HbA1c).

Copyright: © 2018 Dibyajyoti Banerjee . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.