Acta Scientific Microbiology (ISSN: 2581-3226)

Editorial Volume 6 Issue 1

Fourth Dose of COVID-19 Vaccination in Lung Transplant Recipients

Attapon Cheepsattayakorn1,2*, Ruangrong Cheepsattayakorn3 and Porntep Siriwanarangsun1

1Faculty of Medicine, Western University, Pathumtani Province, Thailand

210thZonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand

3Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

*Corresponding Author: Attapon Cheepsattayakorn, 10th Zonal Tuberculosis and Chest Disease Center, Chiang Mai, Thailand.

Received: November 07, 2022; Published: December 01, 2022

Due to immunosuppression, lung or solid-organ-transplant (SOT) patients are at increased risk of infection-related morbidity and mortality, particularly SARS-CoV-2 (COVID-19) infection [1-4]. Dramatically, COVID-19 vaccination changed both immunocompetent- and immunosuppressed-persons landscape [5]. A recent study revealed that SOT recipients with receiving a third dose of COVID-19 vaccination demonstrated improvement of humoral-immune response, compared to patients with receiving two doses [6].


  1. Hallett AM., et al. “SARS-CoV-2 messenger RNA vaccine antibody response and reactogenicity in heart and lung transplant recipients”. The Journal of Heart and Lung Transplantation (2021).
  2. L’huillier AG., et al. “Cell-mediated immune responses after influenza vaccination of solid organ transplant recipients: secondary outcomes analyses of a randomized controlled trial”. The Journal of Infectious Diseases 221 (2020): 53-62.
  3. Mazzone PJ., et al. “The humoral immune response to influenza vaccination in lung transplant patients”. European Respiratory Journal 18 (2001): 971-976.
  4. Scharringa S., et al. “Vaccination and their importance for lung transplant recipients in a COVID-19 world”. Expert Review of Clinical Pharmacology 14 (2021): 1413-1425.
  5. Altneu E and Mishkin A. “COVID-19 vaccination in lung transplant recipients”. Indian Journal of Thoracic and Cardiovascular Surgery 2 (2022): S347-S353.
  6. Efros O., et al. “Efficacy and safety of third dose of the COVID-19 vaccine among solid organ transplant recipients: a systemic review and meta-analysis”. Vaccines 10 (2022): 95.
  7. Caillard S., et al. “Antibody response to a fourth messenger RNA COVID-19 vaccine dose in kidney transplant recipients: a case series”. Annals of Internal Medicine (2022).
  8. Alejo JL., et al. “Antibody response to a fourth dose of a SARS-CoV-2 vaccine in solid organ transplant recipients: a case series”. Transplantation 105 (2021): e280-e281.
  9. Burki TK. “Fourth dose of COVID-19 vaccines in Israel”. Lancet Respiratory Medicine (2022).


Citation: Attapon Cheepsattayakorn., et al. “Fourth Dose of COVID-19 Vaccination in Lung Transplant Recipients". Acta Scientific Microbiology 6.1 (2023): 01.


Copyright: © 2022 Attapon Cheepsattayakorn., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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