Trends in Blood Stream Infections of Adolescents the Forthcoming Challenges in a North Indian Tertiary Care Hospital IGMC Shimla, India
Pankaj Katoch1* and Sanjay Chandel2
1Senior Resident, Department of Microbiology, IGMC Shimla, India
2Assistant Professor, Department of Forensic Medicine, DR. RKGMC Hamirpur, Himachal Pradesh, India
*Corresponding Author: Pankaj Katoch, Senior Resident, Department of Microbiology, IGMC Shimla, India.
Received: October 28, 2021 ; Published: November 24, 2021
Abstract
Background: Septicaemia and bacteremia are among the major challenges faced by health care professionals worldwide, these days leading to increased chances of morbidity and mortality for patients of all age groups.
The incidence among newborns can be low, but the chances of adverse consequences are increased. Blood culture forms a critical part of the evaluation of patients with suspected sepsis [1]. However, very little is known about the trends of bacterial bloodstream infections and antimicrobial susceptibilities among the adolescent population, as the literature is less. Hence, the present study is designed to evaluate the current trends in incidences and the etiological profile of BSI among adolescents using automated Bactec systems
Objective: To formulate guidelines for the care of adolescents from birth to 18 years of age.
Materials and Methods: All blood culture samples received in the Department of Microbiology for culture by Bactec Bd fx from July 2015 to June 2016 were included in the study. The blood culture was observed in the Bactec Bd fx system for at least 5 days before reporting as sterile.
Results: A total of 563 samples in the adolescent age group and suspected of BSI’s received in the Department of Microbiology, IGMC, Shimla. All indoor and outdoor patients with temperatures>=38 degrees C. Among them, 324(57.5%) were of males while 239(42.5%) were females. Among the total of 563 samples, 124(22%) were found to be positive in culture, 426(75.7%) were negative, while 13(2.3%) had contaminants defined by the growth of three different types of colonies in the medium. Among the 124 positive cases, 67(54%) were men while 57(46%) were women.
Conclusion: Bloodstream infection is an important cause of morbidity and mortality in patients of the adolescent age group. All febrile patients in the study group diagnosed with bacterial infections were included in this study. There was relatively high positivity in blood culture among the age group. Positivity was high in males compared to females.
Keywords: Infections; Culture; Bactec; Group of Adolescents
References
- Katoch Pankaj. “Incidence and Etiological Profile of Gram-Positive Bacterial Positivity in Invasive Bloodstream Infections in All Age Groups Using Automated Bactec in Tertiary Care Hospital of North India”. International Academic Journal of Applied Bio-Medical Sciences4 (2021).
- Marta Martín-Fernandez., et al. “Shared Features of Endothelial Dysfunction between Sepsis and Its Preceding Risk Factors (Aging and Chronic Diseases)”. Journal of Clinical Medicine11 (2018): 400.
- Okeke IN., et al. “Antimicrobial resistance in developing countries. Part II: strategies for containment”. The Lancet Infectious Diseases 5 (2005): 568-580.
- Reynolds R., et al. “Antimicrobial susceptibility of the pathogens of bacteremia in the UK and Ireland 2001-2002: the BSAC bacteremia resistance surveillance program”. Journal of Antimicrobial Chemotherapy 53 (2004): 1018-1032.
- Diekema DJ., et al. “Epidemiology and outcome of nosocomial and community-onset bloodstream infection”. Journal of Clinical Microbiology 41 (2003): 3655-3660.
- Parajuli NP., et al. “Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug-Resistant Pathogens”. Canadian Journal of Infectious Diseases and Medical Microbiology (2017): 8763135.
- Larry B., et al. “Bloodstream Infections in Hospitalized Children: Epidemiology and Antimicrobial Susceptibilities”. The Pediatric Infectious Disease Journal5 (2016): 507-510.
- Surbhi Leekha., et al. “General Principles of Antimicrobial Therapy”. Mayo Clinic Proceedings2 (2011): 156-167.
- Seifert H and Wisplinghoff H. “Bacteriology General”. In: Borriello SP, Murray RP, Funke G editors. Topley, and Wilsons Microbiology and Microbiological infections. 10th ed 1 (2001): 509-516.
- Young LS. “Sepsis syndrome”. In: Mandell GL, Mandell JE, Benett JE, Dolin R editors. Principles and practice of infectious diseases, 5thed Churchill Living stone New York (2005): 806-819.
- Wattal C., et al. “Ecology of bloodstream infection and antibiotic resistance in intensive care unit at a tertiary care hospital in North India”. The Brazilian Journal of Infectious Diseases3 (2014): 245-251.
- Malik Shakir Hussain., et al. “Bloodstream infections in the pediatric population in a tertiary care hospital”. International Journal of Contemporary Medical Research2 (2019): B10-B12.
- Meremikwu MM. “Bacterial isolates from blood cultures of children with suspected septicemia in Calabar, Nigeria”. BMC Infectious Diseases 5 (2005): 110.
- Arora U and Devi P. “Bacterial profile of bloodstream infections and antibiotic resistance pattern of isolates”. JK Science 9 (2007): 186-190.
- Murthy DS., et al. “Blood cultures in pediatric patients: a study of clinical impact”. Indian Journal of Medical Microbiology 25 (2007): 220-224.
- Qureshi M and Aziz F. “Prevalence of microbial isolates in blood cultures and their antimicrobial susceptibility profiles”. Biomedica 27 (2011): 136-139.
- Pankaj Katoch. “Bacteriological Profile and Antibiotic Sensitivity Pattern in Early Onset Sepsis and Late-Onset Sepsis and comparison of ampicillin gentamicin combination with regard to 3rd generation cephalosporins for empirical treatment initiation”. International Academic Journal of Applied Bio-Medical Sciences4 (2021): 12-16.
- Donkor ES., et al. “Self-medication practices with antibiotics among tertiary level students in Accra, Ghana: a cross-sectional study”. International Journal of Environmental Research and Public Health10 (2010): 3519-3529.
- Singh Surinder., et al. “Mortality and Morbidity among Children Diagnosed with Ventilator-Associated Pneumonia in Tertiary Care Hospital”. International Academic Research Journal of Internal Medicine and Public Health4 (2021).
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