Ukraine State Enterprise Ukrainian Research Institute for Medicine of Transport, Odessa, Ukraine
*Corresponding Author: Valentina Divocha, Ukraine State Enterprise Ukrainian Research Institute for Medicine of Transport, Odessa, Ukraine.
Received: September 23, 2021 ; Published: October 07, 2021
Present day vaccines have a key role in influenza prophylaxis. Besides, there is a wide spectrum of pharmaceutics: antigrippine I, II, III, amantidin, remantadin, arbidol, laferon, etc. Anti-influenza vaccines and pharmaceutics mentioned above might cause side effects of blood circulating system (thrombocytopenia), immune system (allergic reactions), nervous system (frequent headaches, and less frequently cramps, encephalomyelitis, neuritis, Guillain-Barre syndrome), vascular system (vasculitis with acute damages of renal function).A new generation of antiviral remedies in the form of neuraminidase (zanamivir and oseltamivir) have appeared. They are free of the main drawbacks typical for vaccines and pharmaceutics of amantadin type and cause less resistance in viruses. Domestic scientists used the effect of influenza virus hemaglutine splitting by trypsin-like proteinase of respiratory tract cells of epithelium at two subunits (hemaagglutinin-1 and hemaagglutinin-2) have isolated inhibitor of trypsine-like proteinases which arrested development of influenza in white mice. Now they are searching biological material for isolation of trypsine-like proteinases as anti-virus remedy for a human.
Keywords: Influenza A Virus; Vaccines; Proteinase Ingibitors; Drags
Citation: Valentina Divocha. “Traditional and Prospective Approaches to Influence Prevention”. Acta Scientific Microbiology 4.11 (2021): 11-15.
Copyright: © 2021 Valentina Divocha. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.