Resistance Profile of Aerobic Gram-Negative Bacilli: Study on Pseudomonas aeruginosa and Acinetobacter baumannii in a Tertiary Care Center
Hadi Younes, Laurene Haddad and Jacques Choucair*
Department of Infectious Diseases, Hôtel Dieu de France, Saint Joseph University, Beirut, Lebanon
*Corresponding Author: Jacques Choucair, Department of Infectious Diseases, Hôtel Dieu de France, Saint Joseph University, Beirut, Lebanon.
Received: February 25, 2020 ; Published: August 19, 2021
The natural selection has provided some resistance mechanisms of bacteria or adaptation face some antibiotiques. Or nowadays, overuse of antibiotics and exaggerated in inadequate conditions contributed to the increase in resistance rates. According to the World Health Organization, the resistance of bacteria to antibiotics is a major problem of the twenty-first century. Increasingly, bacteria acquire new resistance mechanisms and arrive to surpass the action of antibiotics. To fight against the proliferation of bacteria, it becomes necessary to find new and effective solutions to this major public health issue.
Keywords: Pseudomonas aeruginosa; Acinetobacter baumannii; Antibiotics
- Eber MR., et al. “Seasonal and temperature-associated increases in gram-negative bacterial bloodstream infections among hospitalized patients”. PLoS One9 (2011): e25298.
- McDonald LC., et al. “Seasonal variation of Acinetobacter infections: 1987-1996. Nosocomial Infections Surveillance System”. Clinical Infectious Diseases 29 (1999): 1133-1137.
- Perencevich EN., et al. “Summer peaks in the incidences of Gram-negative bacterial infection among hospitalized patients”. Infection Control and Hospital Epidemiology 29 (2008): 1124-1131.
- Trent MS. “Biosynthesis, transport, and modification of lipid A”. Biochemistry and Cell Biology 1 (2004): 71-86.
- Maragakis LL and Perl TM. “Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options”. Clinical Infectious Diseases8 (2008): 1254-1263.
- Barros LM., et al. “Prevalência de micro-organismos e sensibilidade antimicrobiana de infecções hospitalares em unidade de terapia intensiva de hospital público no Brasil”. Revista de Ciências Farmacêuticas Básica e Aplicada 3 (2012): 429-435.
- Baumgart AMK., et al. “Prevalence of carbapenem resistant Pseudomonas aeruginosa and Acinetobacter baumannii in high complexity hospital”. Brazilian Journal of Infectious Diseases 5 (2010): 433-436.
- Xu J., et al. “Surveillance and Correlation of Antimicrobial Usage and Resistance of Pseudomonas aeruginosa: A Hospital Population-Based Study”. PLoS ONE11 (2013): e78604.
- Nishant Prasad., et al. “Asymptomatic rectal colonization with carbapenem-resistant Enterobacteriaceae and Clostridium difficile among residents of a long-term care facility in New York City”. American Journal of Infection Control5 (2016): 525-532.
- Otávio Hallal., et al. “Carbapenem-resistant Acinetobacter baumannii contamination in an intensive care unit”. Revista da Sociedade Brasileira de Medicina Tropical 2 (2017): 167-172.
- Dijkshoorn L., et al. “An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii”. Nature Reviews Microbiology 12 (2007): 939-951.
- Mugnier PD., et al. “Worldwide dissemination of the bla OXA-23 carbapenemase gene of Acinetobacter baumannii”. Emerging Infectious Diseases 1 (2010): 35-40.
- Anstey NM., et al. “Community-acquired Acinetobacter pneumonia in the Northern Territory of Australia”. Clinical Infectious Diseases 14 (1992): 83.
- Morrissey I., et al. “A Review of Ten Years of the Study for Monitoring Antimicrobial Resistance Trends (SMART) from 2002 to 2011”. Pharmaceuticals (Basel) 6 (2013): 1335.
- Lim SK., et al. “The outcomes of using colistin for treating multidrug resistant Acinetobacter species bloodstream infections”. Journal of Korean Medical Science 26 (2011): 325.