Current and Prospective Therapeutic Regimens for SARS-CoV-2: Review on Modern Medicine and Alternate Therapies
Shalitha Sasi1, Sindhu Gopinathan Pillai1, Sapna Singh2, Ritu Singhal3, Lokender Kumar3, Imran H Khan4, Aarti Yadav5, Priyanka Bharadwaj5, Prabhakar M5, Sushil Mehta5 and Suresh Thakur5*
1Evidentic GmbH, Martin-Buber-Str. 10, Berlin, Germany
2Safety and Analytical Research Centre (SARC) LLP, Bhat, Ahmedabad, Gujarat, India
3National Reference Laboratory and Center of Excellence (TB) WHO, Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg Near Qutub Minar, Mehrauli, New Delhi, India
4Department of Pathology and Laboratory Medicine, School of Medicine University of California, Davis, CA, USA
5NextGen In-vitro Diagnostics Pvt Ltd., BSC BioNEST Bio-Incubator Regional Centre for Biotechnology, NCR Biotech Cluster, Haryana, India
*Corresponding Author: Suresh Thakur, NextGen In-vitro Diagnostics Pvt Ltd., BSC BioNEST Bio-Incubator Regional Centre for Biotechnology, NCR Biotech Cluster, Haryana, India.
Received: June 28, 2021 ; Published:
The SARS-CoV-2 virus, causative agent of the novel coronavirus disease-19 (COVID-19) continues to spread across the globe with the number of confirmed cases crossing 181 million. Rising human causalities and economic losses due to pandemic calls for a rapid development of vaccines and therapeutics. Research institutes, pharmaceutical companies and governments around the world are focused on accelerating the drug and vaccine development to contain virus and prevent further damage . Many existing broad-spectrum anti-viral and immune-modulatory drugs have been identified to treat disease and associated symptoms. However, their effectiveness is yet to be confirmed by randomized clinical trials. Besides, many countries are also looking into traditional medicines and herbal formulas as an adjunct therapeutic intervention. Furthermore, global race for anti-SARS-CoV-2 vaccine is ongoing, with several candidates are in use and few others progressing to phase 2/3 clinical trials. Here we discuss various promising therapeutic strategies and drugs in-use and under development for treatment and management of COVID-19.
Keywords: COVID-19; SARA-CoV-2; Vaccine; Anti-viral; Alternate Medicine
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