Kulvinder Kochar Kaur¹*, Gautam Allahbadia² and Mandeep Singh³

¹Scientific Director, Dr Kulvinder Kaur Centre for Human Reproduction, Jalandhar, Punjab, India
²Scientific Director, Rotunda-A Centre for Human Reproduction, Mumbai, India
³Consultant Neurologist, Swami Satyan and Hospital, Jalandhar, Punjab, India

*Corresponding Author: Kulvinder Kochar Kaur, Scientific Director, Dr Kulvinder Kaur Centre for Human Reproduction, Jalandhar, Punjab, India.

Received: April 27, 2021 ; Published: June 04, 2021

Type 1 diabetes mellitus (T1D) represents a chronic autoimmune disease (AD) resulting from a complex interplay between genetic proneness and environmental factors. Mostly AD incidence follows a pattern of north-south, with escalated prevalence visualized in countries, such as Finland, Sweden as well as Norway. Gut Microbiota (GM) studies on the implications of extreme climatic environments (like antarctica, time of birth/venue, show impact of extreme cold conditions with no exposure to sunlight thus resulting in Vitamin D deficiency, influence GM composition and immune dysfunction. In case of population from north it is observed that circadian rhythm alterations occur and that have also been illustrated to =>immune dysfunction through a swing in the GM, resulting in AD like T1D [1-5].

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Citation

Citation: Kulvinder Kochar Kaur., et al. “Can Targeting Gut Microbiota in Perinatal Events Aid in Prevention of Type 1 Diabetes Development - Influence T1D Genes Crosstalk with Environmental Factors ”. Acta Scientific Microbiology 4.7 (2021): 11-15.

Copyright

Copyright: © 2021 Kulvinder Kochar Kaur., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.