Acta Scientific Microbiology (ISSN: 2581-3226)

Short Communication Volume 4 Issue 7

Can Targeting Gut Microbiota in Perinatal Events Aid in Prevention of Type 1 Diabetes Development - Influence T1D Genes Crosstalk with Environmental Factors

Kulvinder Kochar Kaur1*, Gautam Allahbadia2 and Mandeep Singh3

1Scientific Director, Dr Kulvinder Kaur Centre for Human Reproduction, Jalandhar, Punjab, India
2Scientific Director, Rotunda-A Centre for Human Reproduction, Mumbai, India
3Consultant Neurologist, Swami Satyan and Hospital, Jalandhar, Punjab, India

*Corresponding Author: Kulvinder Kochar Kaur, Scientific Director, Dr Kulvinder Kaur Centre for Human Reproduction, Jalandhar, Punjab, India.

Received: April 27, 2021 ; Published: June 04, 2021

Type 1 diabetes mellitus (T1D) represents a chronic autoimmune disease (AD) resulting from a complex interplay between genetic proneness and environmental factors. Mostly AD incidence follows a pattern of north-south, with escalated prevalence visualized in countries, such as Finland, Sweden as well as Norway. Gut Microbiota (GM) studies on the implications of extreme climatic environments (like antarctica, time of birth/venue, show impact of extreme cold conditions with no exposure to sunlight thus resulting in Vitamin D deficiency, influence GM composition and immune dysfunction. In case of population from north it is observed that circadian rhythm alterations occur and that have also been illustrated to =>immune dysfunction through a swing in the GM, resulting in AD like T1D [1-5].

References

  1. Kulvinder Kochar Kaur., et al. “An Update on Etiopathogenesis and Management of Type 1 Diabetes Mellitus”. Journal of Endocrinology2 (2017): 1-23.
  2. Kulvinder Kochar Kaur., et al. “Have Probiotics and Synbiotics passed the test of time to be implemented in management of obesity and related metabolic disorders-a comprehensive review”. Advances in Obesity, Weight Management and Control 1 (2019): 21-28.
  3. Kulvinder Kochar Kaur., et al. “Attempting Getting Insulin Independent Immunotherapies in Type 1 Diabetes Mellitus (T1D) in the Pre Stage 1 (BeforeIslet Autoantibodies)”. Acta Scientific Paediatrics6 (2020): 01-04.
  4. Kulvinder Kochar Kaur., et al. “Path Directed towards a Stage when we almost Cure Type1 Diabetes Mellitus (T1dm) after a Century of Insulin Advent”. EC Diabetes and Metabolic Research6 (2020): 37-46.
  5. Kulvinder Kochar Kaur., et al. “Are we any close to unraveling the mechanisms of interactions among Susceptibility genes towards type 1 Diabetes, Gut Microbiota along with Environmental factors –Specifically Early Diet patterns –A Systematic Review?” Endocrinology and Surgical Endocrinology1 (2021): 1-20.
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Citation

Citation: Kulvinder Kochar Kaur., et al. “Can Targeting Gut Microbiota in Perinatal Events Aid in Prevention of Type 1 Diabetes Development - Influence T1D Genes Crosstalk with Environmental Factors ”. Acta Scientific Microbiology 4.7 (2021): 11-15.

Copyright

Copyright: © 2021 Kulvinder Kochar Kaur., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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