Acta Scientific Microbiology (ISSN: 2581-3226)

Review Article Volume 4 Issue 6

Impact of Antiretroviral Treatment on the Plasmatic Viral Load of HIV-1 in Children Followed at the Charles de Gaulle Pediatric University Hospital (CHU-CDG), Ouagadougou Burkina Faso

Mahamoudou Sanou1,2,3,4,5*, Boureima Tangara2, Absatou BA3, Mamadou Tamboura2, Fidele Bakiono5, Bolni Marius Nagalo6, Benoit Kabamba7, Jacques Simpore4 and Rasmata Traore1,2

1University Joseph KI - ZERBO, Ouagadougou, Burkina Faso
2Pediatric University Hospital Charles De Gaulle, Ouagadougou, Burkina Faso
3University Hospital Bogodogo Ouagadougou, Burkina Faso
4Pietro Annigoni Biomolecular Research Center (CERBA), Department of Biochemistry - Microbiology, Burkina Faso
5Military hospital General Lamizana Ouagadougou, Burkina Faso
6Department of Hematology/Oncology, Mayo Clinic Scottsdale, AZ, USA
7AIDS Reference Laboratory, AIDS Reference Laboratory Catholic University of Louvain (UCL), Belgium

*Corresponding Author: Mahamoudou Sanou, University Joseph KI-ZERBO, Ouagadougou, Burkina Faso.

Received: March 03, 2021 ; Published: May 25, 2021

Abstract

Introduction: Despite the improvement in the coverage and effectiveness of Prevention of Mother-to-Child Transmission of HIV (PMTCT) interventions, the pediatric epidemic of HIV infection still persists and the number of PLWHIV in Burkina Faso is estimated at the end of 2018 at 94,000, including 9,400 children under 15 years old.

Objective: The objective of this work is to contribute to better medical care for children under-15 living with HIV-1 by studying the impact of ART on virus replication, through the measurement of viral load ( VL).

Methodologies: This was a retrospective descriptive study carried out at Pediatric University Hospital Charles-de-Gaulle from January 1, 2016 to June 30, 2019. The study included all children under-15 infected with HIV type 1 (HIV-1) and with a plasma viral load measured in the Bacteriology-Virology Department during the study period.

Results: Out of a total of 811 children, 51% were boys, i.e. a sex ratio of 1.03 and nearly 80% of our patients came from the ESTHER project. The most represented age group was [10 - 15] years (50.06%). Among children, 47.3% had a treatment duration greater than or equal to 4 semesters and 43.2% had an undetectable plasma viral load after 4 semesters.

Keywords: HIV-1; PMTCT; Viral Load; ART; CHUP- CDG

References

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Citation

Citation: Mahamoudou Sanou., et al. “Impact of Antiretroviral Treatment on the Plasmatic Viral Load of HIV-1 in Children Followed at the Charles de Gaulle Pediatric University Hospital (CHU-CDG), Ouagadougou Burkina Faso ”. Acta Scientific Microbiology 4.6 (2021): 87-90.

Copyright

Copyright: © 2021 Mahamoudou Sanou., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days
Impact Factor0.614

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