Abstract

The commencement of the 21^st century has witnessed deadly viral infections mainly SARS-CoV and MERS-CoV in 2002 and 2012 subsequently. The current decade further ascended with the emergence of the first outbreak of pneumonia of unknown origin from Wuhan City, China which was later identified exclusively as the epicenter of the disease and later linked to the spread of the disease resulting in pandemic [1]. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. The intermediate source of origin and transfer to humans is not known, however, the rapid human to human transfer has been confirmed widely. There is no clinically approved antiviral drug or vaccine available to be used against COVID-19. However, few broad-spectrum antiviral drugs have been evaluated against COVID-19 in clinical trials, resulted in clinical recovery. In the current review, we summarize and comparatively analyze the emergence and pathogenicity of COVID-19 infection and previous human coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS-CoV). This article gives a brief view about this new virus [2]. Since knowledge about this virus is rapidly evolving and under research, readers are urged to upgrade themselves regularly [3].

Keywords: SARS-CoV-2; COVID-19; MERS-CoV

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Citation

Citation: B Krishna Prasanth., et al. “Emergence of a Novel Virus - A Review Article”. Acta Scientific Microbiology 4.2 (2021): 64-68.

Copyright

Copyright: © 2021 B Krishna Prasanth., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.