Acta Scientific Microbiology (ISSN: 2581-3226)

Research Article Volume 4 Issue 2

Melanin Adhesivity for Possible Trapping of SARS-CoV-2 on Chin Straps: A Proof-of-concept Assay Using Model Nanoparticles †

Juan Carlos Stockert1,2* and Jorge Herkovits3

1Universidad de Buenos Aires, Facultad de Medicina, Instituto de Oncología “Angel H. Roffo”, Area Investigación, Argentina
2Universidad de Buenos Aires, Facultad de Ciencias Veterinarias, Cátedra de Histología y Embriología, e Instituto de Investigación y Tecnología en Reproducción Animal, Argentina
3Instituto de Ciencias Ambientales y Salud, Fundación PROSAMA, Argentina

*Corresponding Author: Juan Carlos Stockert, Universidad de Buenos Aires, Facultad de Medicina, Instituto de Oncología “Angel H. Roffo”, Area Investigación, Argentina.

Received: December 21, 2020; Published: January 22, 2021

×

Abstract

In the frame of COVID-19 pandemic, improved chin straps are obviously necessary to better prevent aerial infection by SARS-CoV-2. Adhesivity of melanins could be applied for trapping virus, but due to present limitations to work with infective agents, we have performed a proof-on-concept assay using zinc oxide (ZnO) nanoparticles with similar size (about 100 nm) as a virus model. Cotton fabrics were impregnated with allomelanin isolated from black beans, and ZnO solutions filtered through melanin-containing filters. Results and controls showed that these filters retained efficiently the nanoparticles, suggesting that melanin-treated chin straps could be a valuable and effective protection resource to trap virus and avoid infection.

Keywords: Aerial Infection; Chin Strap; COVID-19; Melanin Adhesivity; Melanin Coating; SARS-CoV-2; Virus Trapping

×

References

  1. Sahana S., et al. “A venture to discover the treatment of coronavirus disease 2019 (COVID 19): SARS-CoV-2”. Acta Scientific Microbiology 10 (2020): 53-58.
  2. Quan FS., et al. “Universal and reusable virus deactivation system for respiratory protection”. Scientific Reports7 (2017): 39956.
  3. Panzella L., et al. “The late stages of melanogenesis: exploring the chemical facets and the application opportunities”. International Journal of Molecular Sciences 19 (2018):
  4. Solano F. “Melanin and melanin-related polymers as materials with biomedical and biotechnological applications—Cuttlefish ink and mussel foot proteins as inspired biomolecules”. International Journal of Molecular Sciences 7 (2017):1561.
  5. Park J., et al. “Recent advances in melanin-like nanomaterials in biomedical applications: a mini review”. Biomaterials Research 23 (2019):
  6. Mavridi-Printezi A., et al. “Bio-applications of multifunctional melanin nanoparticles: From nanomedicine to nanocosmetics”. Nanomaterials 10 (2020): 2276.
  7. Cavallini C., et al. “Melanin and melanin-like hybrid materials in regenerative medicine”. Nanomaterials 10 (2020): 1518.
  8. Colombo LL., et al. “Photothermal effect by 808-nm laser irradiation of melanin: A proof-of-concept study of photothermal therapy using B16-F10 melanotic melanoma growing in BALB/c mice”. Biomedical Optics Express6 (2019): 2932-2941. 
  9. Liu H., et al. “Melanin-like nanomaterials for advanced biomedical applications: a versatile platform with extraordinary promise”. Advanced Science 7 (2020): 1903129.
  10. d’Ischia M., et al. “Melanins and melanogenesis: from pigment cells to human health and technological applications”. Pigment Cell Melanoma Research 28 (2015): 520-544.
  11. Scognamiglio F., et al. “Adhesive coatings based on melanin-like nanoparticles for surgical membranes”. Colloids and Surfaces. B: Biointerfaces 155 (2017): 553-559.
  12. Król A., et al. “Zinc oxide nanoparticles: Synthesis, antiseptic activity and toxicity mechanism”. Advances in Colloid Interface Science 249 (2017): 37-52.
  13. Mishra PK., et al. “Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications”. Drug Discovery Today12 (2017): 1825-1834.
  14. Land EJ., et al. “Quinone chemistry and melanogenesis”. Methods in Enzymology (2004): 88-109.
  15. Zhou X., et al. “Artificial allomelanin nanoparticles”. ACS Nano10 (2019): 10980-10990.
  16. Liu Y., et al. “Polydopamine and its derivative materials: synthesis and promising applications in energy, environmental, and biomedical fields”. Chemical Review 114 (2014): 5057-5115.
×

Citation

Citation: Juan Carlos Stockert and Jorge Herkovits. “Melanin Adhesivity for Possible Trapping of SARS-CoV-2 on Chin Straps: A Proof-of-concept Assay Using Model Nanoparticles †”. Acta Scientific Microbiology 4.2 (2021): 02-05.




Metrics

Acceptance rate33%
Acceptance to publication20-30 days

Indexed In



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is November 25, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US