Abstract

  Humans have been using natural products for medicinal use for ages. Natural products of therapeutic importance are compounds derived from plants, animals, or any microorganism. Ginger and Turmeric are also used as most commonly used condiments and natural drugs in vogue. These are traditional medicine, having some active ingredients used for the treatment of many diseases and killing of gram negative bacteria as well as gram positive i.e. E. coli, Klebsiella sp. Pseudomonas aeruginosa. Turmeric (Curcuma longa) and ginger (Zingiber officinale) has been used in cooking, and in herbal remedies. It’s possible mechanism of action was examined in terms of antioxidant availability during actual cooking conditions and in therapeutic applications using standardized extracts. The assays involve different levels of serial dilutions of ginger and turmeric and their activity on different stages of killing of bacteria. The aim of this study is to determine whether herbal antibiotics are efficient in their result of mortality in enterobacteriaceae. Aqueous, Methanolic and Ethanolic test extracts of Zingiber officinale and Curcuma longa were prepared. Microbiological tests were employed to determine the zone of inhibition. Standardization of isolates were obtained after incubating for 24 hours. Serial dilutions of Ginger and Turmeric were prepared to measure the OD value and growth of bacteria in the dilutions measured by spectrophotometer. The aqueous extracts of two major preparations of turmeric and ginger, corresponding to its use in cooking and medicine, shows significant antioxidant abilities. The studies reveal that the ability of ginger and turmeric having anti-inflammatory potential that shows susceptibility to gram negative bacteria in ethanol and methanol extract. The OD values of serial dilutions of Turmeric and Ginger determine the ratio of killing of bacteria in different concentrations. Thus it is concluded that Herbal antibiotics have a significant role in killing of bacteria. According to the research it is concluded that due to the excessive usage of medicines it is to be noted that the bacteria are shifting towards more resistancy. However usage of Herbal antibiotics can minimize this effect. Therefore scientists are shifting more towards Herbal medicines as compared to synthetic antibiotics.

Keywords: Turmeric; Ginger; Enterobacteriaceae

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Citation

Citation: Mehwish Saleem., et al. “Study of Herbal Antibiotics Derived from Turmeric and Ginger Applied on Enterobacteriaceae". Acta Scientific Microbiology 3.12 (2020): 07-15.

Copyright

Copyright: © 2020 Mehwish Saleem et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.