Samreen Riaz*

Institute of Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan

*Corresponding Author: Samreen Riaz, Institute of Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan

Received: January 08, 2025; Published: January 21, 2025

Abstract

In Western world the intestinal cancer is becoming more common with time. The adults above the age of 50, and those drinking alcohol are at more risk as compared to others. The scientists are also working on the genetic factors associated with small intestine cancer especially colorectal cancer. Intestinal cancer includes the cancer of small intestinal as well as large intestinal parts. According to studies people affected with these cancers are at risk of getting any second cancer that might be associated with stomach, lungs, vagina or kidneys. As small intestine is directly related to digestive system the most common symptom is abdominal pain and noticeable lump in the abdomen. The treatment includes chemotherapy, 2 line chemotherapy and surgery. However surgery is considered as the pillar curative treatment. And if detected at the early stage the survival rate is increased by 50%.

Keywords: Intestinal Cancer; Phytochemicals; Small Intestinal Cancer

References

1. Medicine UN. Intestinal cancer| “Small intestine cancer” (2020).
2. Society AC. “Survival cases for small intestine (Adenocarcinoma)” (2015).
3. Oncol JG. “Evolution of colorectal cancer”. Colorectal Cancer (2014): 326-335.
4. History of Colorectal cancer. Screening colonoscopes (2016).
5. Mattar M., et al. “Current Management of Inflammatory Bowel Disease and Colorectal Cancer". Gastrointestinal Cancer Research 2 (2010): 53-61.
6. Cancer progress" (2016).
7. Dietz DW. “Consortium for Optimizing Surgical Treatment of Rectal Cancer (OSTRiCh)”. Gastrointestinal Surger (2013).
8. Surgeons A. "National Accreditation Program for Rectal Cancer Is Now Accepting Applications" (2017).
9. World Cancer Report 2014. World Health Organization (2014).
10. Small bowel cancer. (types of small intestinal cancer) (2018).
11. Types (types of large intestinal cancer). Stanford health care (SHC)-stanford medical centre (2019).
12. https://www.cancer.org/cancer/small-intestine-cancer/detection-diagnosis-staging/signs-symptoms.html
13. https://www.webmd.com/cancer/cancer-of-the-small-intestine
14. https://www.cancer.net/cancer-types/small-bowel-cancer/symptoms-and-sign.
15. https://www.summahealth.org/specializedservices/digestive_gastroenterology/conditions-and-treatments/
16. https://www.medicalnewstoday.com/articles/150496
17. https://www.verywellhealth.com/colon-cancer-4014742.
18. Signorelli P., et al. “Natural grape extracts regulate colon cancer cells malignancy”. Nutrition and Cancer3 (2015): 494-503.
19. Cheah KY., et al. “Grape seed extract dose-responsively decreases disease severity in a rat model of mucositis; Concomitantly Enhancing Chemotherapeutic Effectiveness in Colon Cancer Cells”. PLoS ONE1 (2014): e85184.
20. Kim HY., et al. “Antiproliferative crude soy saponin extract modulates the expression of IκBα, protein kinase C, and cyclooxygenase-2 in human colon cancer cells”. Cancer Letters1 (2004): 1-6.
21. Roomi MW., et al. “In vivo antitumor effect of ascorbic acid, lysine, proline and green tea extract on human colon cancer cell HCT 116 xenografts in nude mice: evaluation of tumor growth and immunohistochemistry”. Oncology Reports3 (2005): 421-425.
22. Adams LS., et al. “Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells”. Journal of Agricultural and Food Chemistry3 (2006): 980-985.
23. Tanaka S., et al. “Aged garlic extract has potential suppressive effect on colorectal adenomas in humans”. The Journal of Nutrition3 (2006): 821S-826S.
24. Moghadamtousi SZ., et al. “Annona muricata leaves induce G1 cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells”. Journal of Ethnopharmacology 156 (2014): 277-289.

Citation

Citation: Samreen Riaz. “Intestinal Cancer and Role of Phytochemicals". Acta Scientific Gastrointestinal Disorders 8.2 (2025): 43-49.

Copyright

Copyright: © 2025 Samreen Riaz. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.