Joyce Sanyour¹*, Issa Al Qarshoubi¹, Hasan Al-Sayegh² and Rasha Matar¹

¹Gastroenterology and Hepatology Department, Sultan Qaboos Comprehensive Cancer Care and Research Centre, University Medical City, Muscat, Oman
²MBChB, MPH, Research Laboratories Department, Sultan Qaboos Comprehensive Cancer Care and Research Centre, University Medical City, Muscat, Oman

*Corresponding Author: Gastroenterology and Hepatology Department, Sultan Qaboos Comprehensive Cancer Care and Research Centre, University Medical City, Muscat, Oman.

Received: January 06, 2025; Published: January 19, 2025

Abstract

Background: The objective of the study is to describe the polyps and their characteristics in High-risk Omani population: histopathology, number per patient, location in relation to gender and age at diagnosis. The secondary objective is to evaluate the degree of dysplasia and its relation to the polyps’ locations.

Methods: We conducted a retrospective descriptive study on all specimens of colonic polyps or endoscopically resected polyps from SCCCRC patients over a two-year period from 2022 to 2023. We categorized the patients by age, polyps’ location, and histology. Associations between the polyps’ characteristics were examined.

Results: With 197 endoscopy procedures and 394 polyps removed, 60.4% of the patient are more than 50yo with 1.18 sex ration (M/F). 53.8% had single polyps. Multiple polyps were found to be associated with advanced age, family history, positive genetic study, and FAP histology. Recto-sigmoid colon was the most common location for polyps. In patient age group < 50yo, rectum had the highest proportion of polyps. The older age group (>50yo) had more transverse colon polyps. Concerning histology, adenoma was the most common type without significant correlation between the histological type and the polyps’ location. We found a significant association between histology and genetic pathologies. Nine of our patients had adenocarcinoma/degenerative polyps. Of the 394 polyps, 15 (3.8%) were synchronized cancers, 8 (2%) were Adenocarcinoma degenerative.

Conclusions: This is the first study in the Sultanate of Oman examining the characteristic of colonic polyps. This study gives valuable information about colonic polyp histology and genetic pathology in the Omani population, especially in high-risk groups.

Keywords: Colonic Polyp; Histology; Oman

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Citation

Citation: Joyce Sanyour., et al. “Characteristics of Colonic Polyps in High-risk Omani Population". Acta Scientific Gastrointestinal Disorders 8.2 (2025): 35-42.

Copyright

Copyright: © 2025 Joyce Sanyour., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.