Endoscopic Biliary Drainage of Biliopancreatic Tumors (about 270 Cases)
Samir Mrabti*, Ahlam Benhamdane, Jihane Bennas, Meryem Amine, Tarik Addajou, Reda Berrida, Sara Sentissi, Ilham El Koti, Fedoua Rouibaa and Hassan Seddik
Hepato-Gastro-Enterology Department II of Military Training Hospital Med V in Rabat- Morocco
*Corresponding Author: Samir Mrabti, Hepato-Gastro-Enterology Department II of Military Training Hospital Med V in Rabat- Morocco
Received:
August 09, 2024; Published: January 06, 2025
Abstract
Background: Endoscopic biliary drainage remains the main palliative treatment for biliopancreatic cancers.
The objective of our study was to analyze the results of this drainage technique, as well as the various associated success and failure factors.
Materials and methods: From January 2002 to September 2023, 270 patients with neoplasic biliary stenosis were included in the study. Patients were divided into 3 groups: Group A for patients with proximal cholangiocarcinoma, Group B for patients with pancreatic cancer, and Group C for patients with a gallblader cancer. Only technical success was analyzed. This success was defined as the placement of biliary stent covering the entire stenosis. The factors studied were sex, age, type of cancer, location and appearance of the stenosis, endoscopic dilation of the stenosis before placement of the stent and finally the presence or absence of duodenal stenosis in case of a pancreatic cancer.
Results: The mean age was 64+/-11.2 years. The sex ratio M/F was 1.5. Overall technical success rate was 80%. The analysis according to the type of cancer showed that the success rate was better in pancreatic cancer (81%) compared to cholangiocarcinoma (77%); this diffence wasn’t sigificant in group C which included few patients this rate was 83% .
Conclusion: Palliative endoscopic biliary drainage is an effective method in biliopancreatic cancers. In our study, the important factors associated with success are low located stenosis, the prior dilation of the stenosis and the absence of duodenal stenosis.
Keywords: Biliary Cancer; Pancreatic Cancer ; Gallbladder Cancer ; Endoscopic Retrograde Cholangiopancreatography
References
- Malka D., et al. “Cancer des voies biliaires”. Thésaurus National de Cancérologie Digestive (2023).
- Dumonceau Jean-Marc., et al. “Endoscopic biliary stenting: indications, choice of stent, and results (ESGE Clinical Guidelinese)”. Endoscopy 50 (2018): 910-930.
- Kim JY., et al. “The Comparison of Endoscopic Biliary Drainage in Malignant Hilar Obstruction by Cholangiocarcinoma: Bilateral Metal Stents versus Multiple Plastic Stents”. Gut Liver 6 (2021): 922-929.
- Scheufele F., et al. “Preoperative biliary stenting versus operation first in jaundiced patients due to malignant lesions in the pancreatic head: A meta-analysis of current literature”. Surgery 161 (2017): 939-950.
- Sauvanet A., et al. “Severe Jaundice Increases Early Severe Morbidity and Decreases Long-Term Survival after Pancreaticoduodenectomy for Pancreatic Adenocarcinoma”. J Am Coll Surg 221 (2015): 380-389.
- Crippa S., et al. “Systematic review and meta-analysis of metal versus plastic stents for preoperative biliary drainage in resectable periampullary or pancreatic head tumors 42 (2016): 1278-1285.
- Moole H., et al. “Are self-expandable metal stents superior to plastic stents in palliating malignant distal biliary strictures?” Medical Journal Armed Forces India 73 (2017): 42-48.
- Alain Sauvanet., et al. “Traitement du cancer du pancréas (Recommandation INCa POST’ U” (2019).
- Dumonceau Jean-Marc., et al. “Endoscopic biliary stenting: indications, choice of stent, and results (ESGE Clinical Guidelinese)”. Endoscopy 50 (2018): 910-930.
- Moole H., et al. “Are self-expandable metal stents superior to plastic stents in palliating malignant distal biliary strictures?” Medical Journal Armed Forces India 73 (2017): 42-48.
- Zorrón Pu L., et al. “Endoscopic stenting for inoperable malignant biliary obstruction: a systematic review and meta-analysis”. World Journal of Gastroenterology 21 (2015): 13374-13385.
- Hong WD., et al. “Metal versus plastic stents for malignant biliary obstruction: an update metaanalysis”. Clinics and Research in Hepatology and Gastroenterology 37 (2013): 496-500.
- Sawas T., et al. “Self-expandable metal stents versus plastic stents for malignant biliary obstruction: a meta-analysis”. Gastrointestinal Endoscopy 82 (2015): 256-267.e7.
- Xia MX., et al. “Comparison of endoscopic bilateral metal stent drainage with plastic stents in the palliation of unresectable hilar biliary malignant strictures: Large multicenter study”. Digestive Endoscopy 33 (2021): 179-189.
- Mocan T., et al. “Endoscopic or percutaneous biliary drainage in hilar cholangiocarcinoma: when and how?” World Journal of Gastrointestinal Oncology 13 (2021): 2050-2063.
- Hong WD., et al. “Metal versus plastic stents for malignant biliary obstruction: an update metaanalysis”. Clinics and Research in Hepatology and Gastroenterology 37 (2013): 496-500.
- Anne-Marleen van Keulen., et al. “Success, complication, and mortality rates of initial biliary drainage in patients with unresectable perihilar cholangiocarcinoma”. Surgery Journal 6 (2022): P1606-1613.
- Park JK., et al. “Efficacy of EUS-guided and ERCP-guided biliary drainage for malignant biliary obstruction: prospective randomized controlled study”. Gastrointestinal Endoscopy 88 (2018): 277-282.
- Paik WH., et al. “EUS-guided biliary drainage versus ERCP for the primary palliation of malignant biliary obstruction: a multicenter randomized clinical trial”. American Journal of Gastroenterology 113 (2018): 987- 997.
- Bang JY., et al. “Stent placement by EUS or ERCP for primary biliary decompression in pancreatic cancer: a randomized trial (with videos)”. Gastrointestinal Endoscopy 88 (2018): 9-17.
- Mohan BP., et al. “Endoscopic ultrasoundguided gallbladder drainage, transpapillary drainage,or percutaneous drainage in high risk acute cholecystitis patients : a systematic review and comparative meta-analysis”. Endoscopy 52 (2020): 96-106.
- Bruno Costa Martins., et al. “Ulysses Ribeiro Jr, Fauze Maluf-Filho. Results of endoscopic biliary drainage in patients with malignant hilar stricture”. Clinics 78 (2018): 100153.
- Mitsuru Sugimoto., et al. “Predictive factors for the failure of endoscopic stent-instent self-expandable metallic stent placement to treat malignant hilar biliary obstruction”. World Journal of Gastroenterology34 (2017): 6273-6280.
- Jimme K Wiggers., et al. “Preoperative biliary drainage in perihilar cholangiocarcinoma: identifying patients who require percutaneous drainage after failed endoscopic drainage”. Endoscopy12 (2015): 1124-1131.
- Ariane Vienne MD., et al. “Prediction of drainage effectiveness during endoscopic stenting of malignant hilar strictures: the role of liver volume assessment”. Gastrointestinal Endoscopy 4 (2010): 728-735.
- Saleem A., et al. “Meta-analysis of randomized trials comparing the patency of covered and uncovered self- 103 expandable metal stents for palliation of distal malignant bile duct obstruction”. Gastrointestinal Endoscopy 74 (2011): 321-327.
- Motte S., et al. “Risk factors for septicemia followin gendoscopic biliary stenting”. Gastroenterology 101 (1991): 1374-1381.
- Allison MC., et al. “Antibiotic prophylaxis in gastrointestinal endoscopy”. Gut 58 (2009): 869-880.
- Deviére J., et al. “Les complications du drainage biliaire interne endoscopique”. Acta Endoscopica1 (1986): 19-29.
- Prat F., et al. “Traitement instrumental non chirurgical des pathologies biliaires intra- et extrahépatiques”. EMC-Hépatologie1 (2004): 15-34.
- Cotton P., et al. “Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years”. Gastrointestinal Endoscopy1 (2009): 80-88.
- Boustière C., et al. “Endoscopy and antiplatelet agents.European Society of Gastrointestinal Endoscopy (ESGE) Guideline”. Endoscopy 05 (2011): 445-461.
- Anderson MA., et al. “Complications of ERCP”. Gastrointestinal Endoscopy3 (2012): 467.
- Masci E., et al. “Complications of diagnostic and therapeutic ERCP: a prospective multicenter study”. American Journal of Gastroenterology 96 (2001): 417-423.
- Huibregtse K., et al. “Endoscopic treatment of postoperative biliary stricture”. Endoscopy 18 (1986): 133-137.
- Cotton PB. “Duodenoscopic placement of biliary prothesis in malignant obstructive jaundice”. Gut 22 (1981): A888.
- Dumonceau JM., et al. “Biliary stenting: indications, choice of stents and results: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline”. Endoscopy 44 (2012): 277-298.
- Rey JF., et al. “Recommandation de la société francaise d’endoscopie digestive: protheses biliaires”. Endoscopy 34 (2002): 181-185.
- Laokpessi A., et al. “Traitement endoscopique des sténoses malignes de la voie biliaire principale”. Acta Endoscopica 5 (2004): 728-730.
- Escourrou J., et al. “Consensus en endoscopie digestive (CED)”. Acta Endoscopica2 (2009): 116- 121.
- Dumonceau JM., et al. “Biliary stenting: indications, choice of stents and results: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline”. Endoscopy 44 (2012): 277-298.
- Mallat A., et al. “Fracture of biliary endoproshesis after endoscopic drainage for malignant biliary obstruction. Report of two cases”. Endoscopy 18 (1986): 243-244.
- Xin-Yue Liang., et al. “A Retrospective Study of Biliary Drainage Strategies for Patients with Malignant Hilar Biliary Strictures”. Cancer Management and Research 13 (2021): 4767-4776.
- American Cancer Society. Pancreatic Cancer Early Detection, Diagnosis, and Staging (2018).
- Robert JS Coelen., et al. “Endoscopic versus percutaneous biliary drainage in patients with resectable perihilar cholangiocarcinoma: a multicentre, randomised controlled trial”. Lancet10 (2018): 681- 690.
- Kwang Min Kim., et al. “A Comparison of Preoperative Biliary Drainage Methods for Perihilar Cholangiocarcinoma: Endoscopic versus Percutaneous Transhepatic Biliary Drainage”. Gut and Liver6 (2018).
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