S Salim*, A Bouayad, A Mejait, G Alami, SM Abkari, A Ibrahimi and N Lahmidani

Hepato-Gastroenterology Department, Hassan II University Hospital, Fez, Morocco

*Corresponding Author: S Salim, Hepato-Gastroenterology Department, Hassan II University Hospital, Fez, Morocco.

Received: April 08, 2024; Published: April 26, 2024

Abstract

Splenic abscess is an infectious collection arising from hematogenous or contiguous infections. It is a rare condition, predominantly affecting males and immunocompromised individuals. Currently, there is no consensus regarding the disease's management, including microbiological diagnosis and treatment. The preferred imaging test remains the CT scan, which exhibits excellent sensitivity (95%) and specificity (92%) [1]. It can also facilitate diagnostic punctures. Microbiological diagnosis relies on positive blood cultures, found in 24% to 80% of cases. Abscesses can complicate various immunosuppressive conditions. Diagnosis is often delayed due to clinical and biological presentations mimicking a relapse of the primary pathology [2].
We present the case of a 75-year-old woman diagnosed with ischemic heart disease in 2021 under treatment; the patient was recently diagnosed with primary biliary cholangitis (PBC) in March 2023, leading to the initiation of ursodeoxycholic acid (UDCA) at a dose of 13 mg/kg, resulting in significant clinical and biochemical improvement; The patient presented with a febrile syndrome, four months after the diagnosis of PBC; after all the necessary biological tests and additional examinations ; the diagnosis of a splenic abscess was confirmed, the patient was put on antibiotic therapy with good clinical and biological improvement.

Keywords: Primary Biliary Cholangitis (PBC);

References

1. Vilde JL. “Pathophysiology of infections after splenectomy”. Chirurgie 102 (1982): 322-326.
2. Echarrab M., et al. “Abscesses of the spleen. A propos de 10 observations”. Médecine du Maghreb 85 (2001): 55-57.
3. Gassaye D., et al. “Abscesses of the spleen. A propos de 13 cas”. Médecine d'Afrique Noire 1 (2000): 41-43.
4. Loussaief C., et al. “Pyogenic abscesses of the spleen. A propos de 8 cas”. La revue de Médecine Interne 7 (2005): 541-544.
5. Fall B., et al. “Abscesses of the spleen in 5 cases”. Chir 128 (1991): 256-259.
6. Chun CH., et al. “Splenic abscess”. Medicine 59 (1980): 60-65.
7. Ki-Zerbo GA., et al. “Salmonella typhi splenic abscess: à propos d'une observation au CHNSS de BoboDioulasso”. Médecine d'Afrique Noire 5 (1999): 283-285.
8. Gleich S., et al. “A review of percutaneous drainage in splenic abcess”. Surgery, Gynecology and Obstetrics 167 (1986): 211-215.
9. Delattre JF., et al. “Percutaneous drainage in collections of the abdomen”. Emémoires de l'Académie Nationale de Chirurgie 2 (2003): 50-54.
10. Rotman N., et al. “Abscesses of the spleen: diagnosis and treatment. A propos de 12 cas”. Annales de Chirurgie 3 (1989): 203-206.
11. Kyaw MH., et al. “Evaluation of severe infections and survival after splenectomy”. The American Journal of Medicine 119 (2006): 276-282.
12. Beytout J., et al. “Asplenia and hyposplenia”. Presse Medicine 32 (2003): 355-359.
13. Legrand A., et al. “Prévention du risque postoperative infection in splenectomized patients”. Annales Françaises d'Anesthésie et de Réanimation 24 (2005): 807-813.
14. Dumont J. “Infections after splenectomy: vigilance is still required”. Hématologie 2 (2006): 9.

Citation

Citation: S Salim., et al. “Case Report: Splenic Abscess complicating a Primary Biliary Cholangitis (PBC) - A Rare Clinical presentation". Acta Scientific Gastrointestinal Disorders 7.5 (2024): 13-16.

Copyright

Copyright: © 2024 S Salim., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.