Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Case Report Volume 7 Issue 5

Case Report: Acute Hemorrhagic Colitis Following Doxorubicin Chemotherapy

S Salim*, R Eljim, A Mejait, M Abkari, A Ibrahimi and N Lahmidani

Hepato-Gastroenterology Department, Hassan II University Hospital, Fez, Morocco

*Corresponding Author: S Salim, Hepato-Gastroenterology Department, Hassan II University Hospital, Fez, Morocco.

Received: April 08, 2024; Published: April 25, 2024

Abstract

Systemic treatments employed in oncology, including cytotoxic agents and targeted therapies, often lead to gastrointestinal side effects. The severity of colitis and its potential complications necessitate prompt diagnosis and appropriate management. We present the case of a 70-year-old, he was diagnosed since May 2023 for a dedifferentiated liposarcoma on the 10th left rib put on chemotherapy based on D-Rubicin 90mg; and who presented five days after the first course of treatment a severe bloody diarrhea with haemodynamic instability; the patient benefited from an upper and lower digestive endoscopy having objectified revealed two ulcers with thickened irregular margins and fibrinous background, centered on regenerative areas. Biopsies confirmed subacute colitis with non-specific epithelial abnormalities; doxorubicin was halted, and the patient was kept under clinical surveillance with transfusion and corticosteroid enema with good clinical improvement..

Keywords: Acute Hemorrhagic, Colitis, Doxorubicin, Chemotherapye

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Citation

Citation: S Salim., et al. “Case Report: Acute Hemorrhagic Colitis Following Doxorubicin Chemotherapy". Acta Scientific Gastrointestinal Disorders 7.5 (2024): 09-12.

Copyright

Copyright: © 2024 S Salim., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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