Rajeev Gupta*

Consultant Paediatrician, Chairman Central Specialist Committee Royal College of Paediatrics and Child Health, Barnsley Foundation Hospital, United Kingdom

*Corresponding Author: Rajeev Gupta, Consultant Paediatrician, Chairman Central Specialist Committee Royal College of Paediatrics and Child Health, Barnsley Foundation Hospital, United Kingdom.

Received: July 24, 2023; Published: October 06, 2023

Abstract

Inflammatory Bowel Disease (IBD), encompassing Crohn's disease and ulcerative colitis, represents a group of chronic and often debilitating conditions. The therapeutic landscape of IBD has transformed over the past decades, evolving from the use of corticosteroids and immunomodulators to targeted biologics and small molecule inhibitors. However, choosing the appropriate treatment remains a challenging clinical decision, given the variability in patient responses, the potential for side effects, high costs, and varying administration routes. This comprehensive review and meta-analysis aims to review and analyse recent studies on the efficacy, safety, and cost-effectiveness of different IBD treatment regimens. The results indicate that while newer therapies have significantly improved disease outcomes and quality of life, issues such as side effects, loss of response over time, high costs, and administration challenges persist. These findings highlight the need for further research to refine current treatment strategies, enhance our understanding of disease pathogenesis, and move towards personalized medicine in IBD management. Importantly, the rising global prevalence and associated costs of IBD underscore the urgency for more accessible and effective treatments. In conclusion, the journey towards the ideal IBD treatment, which is safe, efficacious, cost-effective, and tailored to individual patient needs, is ongoing, and continued research is vital in bringing us closer to this goal.

Keywords: Meta-Analysis; Regimens; Inflammatory Bowel Disease; Costs; Future Direction

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Citation

Citation: Rajeev Gupta. “Comprehensive Review and Meta-Analysis of Management Regimens for Inflammatory Bowel Disease Including the Costs and Future Direction".Acta Scientific Gastrointestinal Disorders 6.11 (2023): 11-18.

Copyright

Copyright: © 2023 Rajeev Gupta. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.