Solid Pseudopapillary Tumor of the Pancreas: Clinical Characteristics
Maxim N Peshkov1* and Igor V Reshetov2
1Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, Russia
2I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
*Corresponding Author: Maxim N Peshkov, Federal Research and Clinical Center of Specialized Medical Care and Medical Technologies FMBA of Russia, Moscow, Russia.
Received:
November 4, 2022; Published:
December 12, 2022
Abstract
Solid pseudopapillary pancreatic tumor (SPTP) is a rare heterogeneous pancreatic tumor with multicentric growth and low malignancy potential, with favorable prognosis after surgical treatment. A small percentage of patients exhibit aggressive behavior. The histogenesis of these epithelial neoplasms remains unclear, although it is likely that they originate from pluripotent immature cells of the pancreas. Grade criteria for SPTP have not been established. The prognosis of SPTP is generally favorable, with patients having a chance of long-term survival even with relapses and/or metastases after radical surgery.
The tumor is usually large and invariably a capsule. The diagnosis in most cases is based on symptoms of compression, pain, or detection of a palpable mass, while in about 20% of patients, detection is "incidental" during abdominal imaging performed for other conditions. CT and MRI are not always sufficient to distinguish this tumor type with certainty from other cystic neoplasms of the pancreas, such as pseudocysts, parasitic cysts, and congenital cysts. Cytological examination in most cases allows the diagnosis of SPTP. The malignancy of these neoplasms is not high and is determined by capsular invasion, proliferation of lymph nodes and, only in rare cases, metastases to the liver and peritoneum. Surgical treatment should be radical, since a malignant neoplasm can only be determined by postoperative histological examination.
This article reviews the clinical, pathological and visual characteristics of solid pseudopapillary pancreatic tumor (SPTP) used in routine clinical practice.
Keywords: Pancreas; Solid Pseudopapillary Tumour; Malignancy; Metastasis; Pancreas; Surgery; Multicentric Lesions; Solid Pseudopapillary Neoplasm; CT
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