Bobomuratov Turdikul Akramovich*, Rakhmanova Lola Karimovna and Samadov Abdukakhkhor Abdurakhmonovich

Tashkent Medical Academy, Uzbekistan

*Corresponding Author: Bobomuratov Turdikul Akramovich, Tashkent Medical Academy, Uzbekistan.

Received: July 12, 2022; Published: September 26, 2022

Abstract

In order to study the effect of helicobacter pylori on gastric and duodenal dysfunction in nephrotic syndrome in children, 126 children aged 7 to 17 years with various clinical variants of nephrotic syndrome were under our observation. The results of the study revealed that the detection rate of Helicobacter pylori in children with nephrotic syndrome largely depends on the depth of gastric and duodenal mucosa damage. It is detected in hypertrophic and erosive gastritis in 46 (71.8%) cases, in superficial changes in 18 (28.2%) cases. The HELIK-test is a simple and informative method for diagnosing Helicobacter pylori infection in gastric and duodenal disorders in children with nephrotic syndrome, it is convenient for medical practice and recommended for use in the primary examination of the patient, dynamic monitoring and monitoring of the effectiveness of therapy.

Keywords: Nephrotic Syndrome; Helicobacter Pylori; Children

References

1. Jdanova OA. “Glucocorticosteroid therapy and physical development of children with steroid-sensitive nephrotic syndrome: results of a retrospective study”. VSP 4 (2017): 291-293.
2. Karimdjanov IA and Israilova NA. “Chronic kidney disease in children (literature review)”. Health of the Child 7 (2017): 832-835.
3. Nyrkova PA and Savenkova ND. “Studies of the effectiveness of cytostatic therapy for frequently relapsing, hormone-dependent and steroid-toxic nephrotic syndrome in children”. Nephrology 1 (2017): 30-40.
4. Obukhova VA and Dlin VV. “Risk factors for the often relapsing course of steroid-sensitive nephrotic syndrome in children”. Russian Bulletin of Perinatology and Pediatrics6 (2017): 79-83.
5. Postnikov SS., et al. “Drug damage to the kidneys”. Pediatrics. Speransky 4 (2016): 167-173.
6. Kondoh T., et al. “Assessment of factors associated with mizoribine responsiveness in children with steroid-dependent nephrotic syndrome”. Clinical and Experimental Nephrology9 (2019): 1154-1160.
7. Mizutani A., et al. “Positive effects of single-daily high-dose mizoribine therapy after cyclophosphamide in young children with steroid-dependent nephrotic syndrome”. Clinical and Experimental Nephrology2 (2019): 244-250.
8. Rakhmanova LK., et al. “Immuno- hematological risks of chronic kidney disease in children with limfatic diathesis”. Journal of Xi'an Shiyu University, Natural Science Edition. 16.10 (2020).
9. Rakhmanova LK., et al. “Peculiarities of immunity in neurotic syndrome in children with covid-19 against the atopic background”. Turkish Journal of Phisiotherapy and Rehabilitation2 (2021): 4391-4394.297-311.
10. Rakhmanova LK., et al. “Risk factors for the development of kidney amiloidosis in children”. New Day in Medicine38/1 (2021): 194-200.
11. Schijvens AM., et al. “Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndrome”. Pediatric Nephrology3 (2019): 389-403.
12. Zachwieja J., et al. “Multicenter analysis of the efficacy and safety of a non-standard immunosuppressive therapy with rituximab in children with steroid-resistant nephrotic syndrome”. Clinical and Experimental Pharmacology and Physiology4 (2019): 313-321.

Citation

Citation: Bobomuratov Turdikul Akramovich., et al. “Effect of Helicobacter Pylori in Children with Nephrotic Syndrome to the Dysfunction of Stomach and Duodenum". Acta Scientific Gastrointestinal Disorders 5.10 (2022): 21-24.

Copyright

Copyright: © 2022 Bobomuratov Turdikul Akramovich., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.