Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Short Communication Volume 5 Issue 9

Surgical Care for Gastro-Intestinal Stromal Tumours

Patnala Mohan Patro*

Former Professor and HOD of Surgery, GIMSR, GITAM University, India

*Corresponding Author: Patnala Mohan Patro, Former Professor and HOD of Surgery, GIMSR, GITAM University, India.

Received: July 21, 2022; Published:

Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract [1]. GISTs are usually found in the stomach or small intestine but can occur anywhere along the GI tract and rarely have extra-GI involvement.

 

Surgery is the definitive therapy for localized GISTs [2]. Despite the proven success of Imatinib and other newer tyrosine kinase inhibitors, surgical resection remains the treatment of choice and offers the only chance for cure of GIST [3].

References

  1. PDQ Adult Treatment Editorial Board. “Gastrointestinal Stromal Tumors Treatment (Adult) (PDQ®)”. Health Professional Version (2020).
  2. Casli PG., et al. “ESMO Guidelines Committee, EURACAN and GENTURIS. Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up”. Annals of Oncology 1 (2022): 20-33.
  3. Guo Y., et al. “The Role of Surgical Resection Following Tyrosine Kinase Inhibitors Treatment in Patients with Advanced Gastrointestinal Stromal Tumors: A Systematic Review and Meta-analysis”.Journal of Cancer 23 (2019): 5785-5792.
  4. Katai H., et al. “Wedge resection of the stomach for gastric leiomyosarcoma”. British Journal of Surgery4 (1997): 560-561.
  5. National Comprehensive Cancer Network. “NCCN Clinical Practice Guidelines in Oncology: Gastrointestinal Stromal Tumors (GISTs)”. NCCN.
  6. Zhao Y., et al. “Retrospective Comparison of Endoscopic Full-Thickness Versus Laparoscopic or Surgical Resection of Small (≤ 5 cm) Gastric Gastrointestinal Stromal Tumors”. Journal of Gastrointestinal Surgery12 (2019): 2714-2721.
  7. Eisenberg BL and Judson I. “Surgery and imatinib in the management of GIST: emerging approaches to adjuvant and neoadjuvant therapy”.Annals of Surgical Oncology5 (2004): 465-475.
  8. Rutkowski P., et al. “Surgical treatment of patients with initially inoperable and/or metastatic gastrointestinal stromal tumors (GIST) during therapy with imatinib mesylate”. Journal of Surgical Oncology4 (2016): 304-311.
  9. Chen H., et al. “Complete hepatic resection of metastases from leiomyosarcoma prolongs survival”. Journal of Gastrointestinal Surgery 2 (1998): 151-155.

Citation

Citation: Patnala Mohan Patro. “Surgical Care for Gastro-Intestinal Stromal Tumours". Acta Scientific Gastrointestinal Disorders 5.9 (2022): .

Copyright

Copyright: © 2022 Patnala Mohan Patro. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days

Indexed In




News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is December 15, 2022.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of “Best Article of the Issue”.
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.
  • Contact US