Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Editorial Volume 5 Issue 8

The Cannulated Amalgamation-Tubular Adenoma

Anubha Bajaj*

Department of Histopathology, Panjab University/A.B. Diagnostics, India

*Corresponding Author: Anubha Bajaj, Department of Histopathology, Panjab University/A.B. Diagnostics, India.

Received: June 22, 2022; Published: July 01, 2022


Tubular adenoma is denominated as a neoplastic polyp associated with low grade epithelial dysplasia. Preponderantly emerging within colon, tubular adenoma may configure as a precursor to invasive adenocarcinoma of colorectal region. Singular tubular adenoma is characteristically associated with an estimated < 25% villous component. Tumefaction may be incidentally discerned upon colonoscopy [1,2]. Enhanced consumption of fruits, dietary fibre or folate decimates proportionate metamorphosis of tubular adenoma or possible emergence of conventional colorectal adenoma [1,2]. Tubular adenoma is commonly encountered in individuals >50 years wherein disease incidence is enhanced in elderly individuals. A male predominance is observed. Generally, lesions are common within left colon comprising of left half of transverse colon, splenic flexure, descending colon and sigmoid colon along with rectum [1,2]. Tubular adenoma exhibits a distinctive spectrum of metamorphosis from adenoma to carcinoma comprised of genetic mutations within KRAS, TP53 and APC genes besides β-catenin. Genetic mutations of KRAS appear preponderant in tubular adenomas [1,2].


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  2. Myers DJ and Arora K. “Villous Adenoma”. Stat Pearls International. Treasure Island, Florida (2021).
  3. Imperiale TF., et al. “Prevalence of Advanced, Precancerous Colorectal Neoplasms in Black and White Populations: A Systematic Review and Meta-analysis”. Gastroenterology 6 (2018): 1776-1786 e1.
  4. David Y., et al. “Confounders in Adenoma Detection at Initial Screening Colonoscopy: A Factor in the Assessment of Racial Disparities as a Risk for Colon Cancer”. Journal of Cancer Research and Therapeutics 4 (2019): 269-289.
  5. Image 1 Courtesy:
  6. Image 2 Courtesy: Research gate.


Citation: Anubha Bajaj. “The Cannulated Amalgamation-Tubular Adenoma". Acta Scientific Gastrointestinal Disorders 5.8 (2022): 01-02.


Copyright: © 2022 Anubha Bajaj. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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