Lakshmi Shanmugam¹, Kamali Doss², Soundarya Rajamanickam³, Niranjan Biswal⁴ and Jharna Mandal⁵*

¹M.D Microbiology, Senior Resident, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
²M. Sc, Research Scholar, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
³MBBS, Junior Resident, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
⁴M.D Pediatrics, Professor (senior scale), Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
⁵M.D Microbiology, Professor, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India

*Corresponding Author: Jharna Mandal, M.D Microbiology, Professor, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Received: May 27, 2022; Published:

Abstract

Background: Shigellosis is one of the leading causes of mortality and morbidity among children less than five years (under-5 children). Available literature report Atypical serotypes of Shigella flexneri from various parts of the world. At present, there are 17 serotypes in S. dysenteriae, 6 serotypes and 14 subserotypes in S. flexneri, 20 serotypes in S. boydii and a single serotype of S.sonnei, 2 phases and 5 biotypes (a, b, e, f and g). Here, we report a strain of mannitol non-fermenting S.flexneri serotype 4 in a one-year-old girl child presented with high-grade fever and loose stools.

Clinical Description: A one-year-old girl child with a known history of absence seizures presented with high-grade fever and loose stools for two days, about 8-9 episodes per day, foul-smelling, mucoid in nature, stained with fresh blood, and abdominal pain. The child also had 2-3 episodes of vomiting, non-bilious, non-blood-stained and contained food particles. Stool sample was plated onto MacConkey agar (MAC) and Xylose Lysine Deoxycholate Agar (XLD agar) and incubated aerobically at 37°C for 16-18 hours.Non lactose fermenting and red colonies were seen in MAC and XLD respectively which was identified subsequently as Shigella flexneri by serogrouping, but was a mannitol non fermentor. The isolate was found to harbour multiple virulence genes by PCR.

Conclusion: The child was continued on oral cefixime for 10 days but has not improved following which she was started on Inj. Ceftriaxone 100 mg/kg/day for 5 days and the child improved and discharged subsequently.

Keywords: Atypical Shigella; Type IV Shigella Flexneri; Non-Mannitol Fermentor; Shigellosis; Virulence Genes PCR

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Citation

Citation: Jharna Mandal., et al. “A Case Report of Dysentery Caused by an Unusual Shigella Isolate from South India". Acta Scientific Gastrointestinal Disorders 5.7 (2022): 00-00.

Copyright

Copyright: © 2022 Jharna Mandal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.