Lakshmi Shanmugam1, Kamali Doss2, Soundarya Rajamanickam3, Niranjan Biswal4 and Jharna Mandal5*
1M.D Microbiology, Senior Resident, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
2M. Sc, Research Scholar, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
3MBBS, Junior Resident, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
4M.D Pediatrics, Professor (senior scale), Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
5M.D Microbiology, Professor, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
*Corresponding Author: Jharna Mandal, M.D Microbiology, Professor, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Received: May 27, 2022; Published:
Background: Shigellosis is one of the leading causes of mortality and morbidity among children less than five years (under-5 children). Available literature report Atypical serotypes of Shigella flexneri from various parts of the world. At present, there are 17 serotypes in S. dysenteriae, 6 serotypes and 14 subserotypes in S. flexneri, 20 serotypes in S. boydii and a single serotype of S.sonnei, 2 phases and 5 biotypes (a, b, e, f and g). Here, we report a strain of mannitol non-fermenting S.flexneri serotype 4 in a one-year-old girl child presented with high-grade fever and loose stools.
Clinical Description: A one-year-old girl child with a known history of absence seizures presented with high-grade fever and loose stools for two days, about 8-9 episodes per day, foul-smelling, mucoid in nature, stained with fresh blood, and abdominal pain. The child also had 2-3 episodes of vomiting, non-bilious, non-blood-stained and contained food particles. Stool sample was plated onto MacConkey agar (MAC) and Xylose Lysine Deoxycholate Agar (XLD agar) and incubated aerobically at 37°C for 16-18 hours.Non lactose fermenting and red colonies were seen in MAC and XLD respectively which was identified subsequently as Shigella flexneri by serogrouping, but was a mannitol non fermentor. The isolate was found to harbour multiple virulence genes by PCR.
Conclusion: The child was continued on oral cefixime for 10 days but has not improved following which she was started on Inj. Ceftriaxone 100 mg/kg/day for 5 days and the child improved and discharged subsequently.
Keywords: Atypical Shigella; Type IV Shigella Flexneri; Non-Mannitol Fermentor; Shigellosis; Virulence Genes PCR
Citation: Jharna Mandal., et al. “A Case Report of Dysentery Caused by an Unusual Shigella Isolate from South India". Acta Scientific Gastrointestinal Disorders 5.7 (2022): 00-00.
Copyright: © 2022 Jharna Mandal., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.