Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Review Article Volume 5 Issue 5

Oxidative Stress in Pregnant Women and Low Birth Weight

Rodolfo Nuñez-Musa1* and Alberto J Nuñez-Sellés2

1Contract Research Organization DR (CREODR), MSc, Senior Researcher, Clinical Coordinator at OyMed School of Medicine, Dominican Republic
2Contract Research Organization DR (CREODR), PHD, Senior Researcher, Consultant Researcher at Pedro Henriquez Ureña University, Dominican Republic

*Corresponding Author: Rodolfo Nuñez-Musa, Contract Research Organization DR (CREODR), MSc, Senior Researcher, Clinical Coordinator at OyMed School of Medicine, Dominican Republic.

Received: February 21, 2022; Published: April 22, 2022



The growth of the child during pregnancy is the result of the interaction of socioeconomic elements, demographic background and health of the family and mother with the inherent biological process. Many factors exert their influence, even before pregnancy, leading to physiological changes that determine some disruptions in the way to full fetal maturation. Oxidative stress is implicated in the pathophysiology of many complications during pregnancy including miscarriage, hypertensive disorders, fetal growth and development disarrays and prematurity. Due to an excess of reactive oxygen species, cellular and biochemical damage make up a severe threat to the well-being of the mother and child, since the protection of the antioxidant system is often deteriorated and is incapable to maintain cellular membrane integrity. Oxidative stress causing this harm has been widely evidenced and poorly understood yet.  The potential use of supplementation with antioxidants trying to stop or reverse the oxidative damage, still requires a definition of standard diagnostic criteria and a exhaustive understanding of the mechanism of action.

The aim of this review is to focus the current knowledge on oxidative stress, oxidative stress biomarkers and their relationship with pregnancy outcomes.


Keywords: Pregnancy Outcome; Mother-Child Binomial; Oxidative Stress; Micronutrients; Complications



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Citation: Rodolfo Nuñez-Musa and Alberto J Nuñez-Sellés. “Oxidative Stress in Pregnant Women and Low Birth Weight". Acta Scientific Gastrointestinal Disorders 5.5 (2022): 20-29.


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