Punitkumar Patel¹, Arun Bahulikar², Nandakumar Beke³, Divya Patel⁴ and Deepak Phalgune⁵*

¹Senior resident, Department of Medicine, Poona Hospital and Research Centre, Pune, India

⁵Research Consultant, Department of Research, Poona Hospital and Research Centre, Pune, India

*Corresponding Author: Deepak Phalgune, Research Consultant, Department of Research, Poona Hospital and Research Centre, Pune, India.

Received: November 29, 2021; Published: December 23, 2021

Abstract

Background: There are little data in the literature on the sensitivity of the urine trypsinogen 2 (UT-2) test in the diagnosis of acute pancreatitis, and results have been controversial. Also, studies of UT-2 test in the Indian population are few in number. The aim of the present study was to find the sensitivity and specificity of UT- 2 dipstick test for the diagnosis of acute pancreatitis in acute upper abdominal pain patients.

Material and Methods: One hundred-sixty-six patients aged between 18 and 80 years presenting with acute abdominal pain were included for this cross-sectional observational study. All the patients were tested with UT-2 dipstick test, serum amylase, serum lipase. Ultrasonography or contrast-enhanced computed tomography of abdomen was performed simultaneously. The diagnostic efficacy index such as sensitivity, specificity, positive predictive value, negative predictive value was calculated using the appropriate gold standard.

Results: The sensitivity and specificity of UT-2 dipstick test for detecting acute pancreatitis were 90.7% and 87.5% respectively. The sensitivity and specificity of serum amylase for detecting acute pancreatitis were 61.1% and 100.0% respectively. The sensitivity and specificity of serum lipase for detecting acute pancreatitis were 81.5% and 100.0% respectively.

Conclusions: The UT-2 test had good sensitivity and specificity and can be used reliably for the diagnosis of acute pancreatitis in acute upper abdominal pain.

Keywords: Acute Upper Abdominal Pain; Acute Pancreatitis; Sensitivity; Specificity; Urine Trypsinogen 2 Test

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Citation

Citation: Deepak Phalgune., et al. “Sensitivity and Specificity of Urine Trypsinogen 2 Dip Test in Acute Upper Abdominal Pain for the Diagnosis of Acute Pancreatitis". Acta Scientific Gastrointestinal Disorders 5.1 (2022): 31-35.

Copyright

Copyright: © 2022 Deepak Phalgune., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.