Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Research Article Volume 5 Issue 1

Sensitivity and Specificity of Urine Trypsinogen 2 Dip Test in Acute Upper Abdominal Pain for the Diagnosis of Acute Pancreatitis

Punitkumar Patel1, Arun Bahulikar2, Nandakumar Beke3, Divya Patel4 and Deepak Phalgune5*

1Senior resident, Department of Medicine, Poona Hospital and Research Centre, Pune, India

2HoD and Consultant Physician, Department of Medicine, Poona Hospital and Research Centre, Pune, India

3Consultant Physician, Poona Hospital and Research Centre, Pune, India

4HoD, Department of Pathology, Poona Hospital and Research Centre, Pune, India

5Research Consultant, Department of Research, Poona Hospital and Research Centre, Pune, India

*Corresponding Author: Deepak Phalgune, Research Consultant, Department of Research, Poona Hospital and Research Centre, Pune, India.

Received: November 29, 2021; Published: December 23, 2021

Abstract

Background: There are little data in the literature on the sensitivity of the urine trypsinogen 2 (UT-2) test in the diagnosis of acute pancreatitis, and results have been controversial. Also, studies of UT-2 test in the Indian population are few in number. The aim of the present study was to find the sensitivity and specificity of UT- 2 dipstick test for the diagnosis of acute pancreatitis in acute upper abdominal pain patients.

Material and Methods: One hundred-sixty-six patients aged between 18 and 80 years presenting with acute abdominal pain were included for this cross-sectional observational study. All the patients were tested with UT-2 dipstick test, serum amylase, serum lipase. Ultrasonography or contrast-enhanced computed tomography of abdomen was performed simultaneously. The diagnostic efficacy index such as sensitivity, specificity, positive predictive value, negative predictive value was calculated using the appropriate gold standard.

Results: The sensitivity and specificity of UT-2 dipstick test for detecting acute pancreatitis were 90.7% and 87.5% respectively. The sensitivity and specificity of serum amylase for detecting acute pancreatitis were 61.1% and 100.0% respectively. The sensitivity and specificity of serum lipase for detecting acute pancreatitis were 81.5% and 100.0% respectively.

Conclusions: The UT-2 test had good sensitivity and specificity and can be used reliably for the diagnosis of acute pancreatitis in acute upper abdominal pain.

Keywords: Acute Upper Abdominal Pain; Acute Pancreatitis; Sensitivity; Specificity; Urine Trypsinogen 2 Test

References

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Citation

Citation: Deepak Phalgune., et al. “Sensitivity and Specificity of Urine Trypsinogen 2 Dip Test in Acute Upper Abdominal Pain for the Diagnosis of Acute Pancreatitis". Acta Scientific Gastrointestinal Disorders 5.1 (2022): 31-35.

Copyright

Copyright: © 2022 Deepak Phalgune., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




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