Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Research Article Volume 4 Issue 11

The State of the Organs of the Hepatopancreatobiliary System and the Quality of Life After Cholecystectomy

EI Mitusheva1*, RG Sayfutdinov2 and RSH Shaimardanov3

1Candidate of Medical Science, Assistant of the Department of Hospital and Polyclinic Therapy, Russia
2Doctor of Medical Science, Professor of the Department of Hospital and Polyclinic Therapy, Russia
3Candidate of Medical Science, Professor of the Department of Surgery, Russia

*Corresponding Author: EI Mitusheva, Kazan State Medical Academy - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Healthcare of the Russian Federation, Russia.

Received: September 30, 2021; Published: October 28, 2021



Objective: To assess the quality of life of patients and the state of the hepatopancreatobiliary system before and after cholecystectomy in the long-term period.

Materials and Methods: The 107 people were examined after emergency and planned cholecystectomy (with symptomatic and asymptomatic course of cholelithiasis).

Results: The majority of patients, regardless of the type of surgery, had symptoms of dyspepsia associated with the development of functional disorders of the gastrointestinal tract (gastroesophageal reflux, duodenogastric reflux, sphincter Oddi dysfunction).

Conclusion: After cholecystectomy, functional disorders of the digestive system predominate in the long-term period due to loss of the physiological function of the gallbladder.

Keywords: Gallbladder Removal; Cholecystectomy; Quality of Life



  1. Minushkin ON. “Sindrom posle kholetsistektomii v praktike terapevta i gastroenterologa [Syndrome after cholecystectomy in the practice of a therapist and gastroenterologist]”. Lechashii vrach - Attending Physician 2 (2015): 40-47.
  2. Il'chenko AA. “Bolezni zhelchnogo puziria i zhelchnikh putei: Rukovodstvo dlia vrachei. [Diseases of the gallbladder and biliary tract: A Guide for Physicians]”. Moscow, MIA Publ., (2011): 880.
  3. Il'chenko AA. “Pochemu kholetsistektomia ne vsegda uluchshaet kachestvo zhizni? [Why cholecystectomy doesn't always improve quality of life?]”. Pharmateka – Pharmateca 17 (2012): 23-29.
  4. Lazebnik LB., et al. “Sravnitel'noe issledovanie kachestva zhizni u bol'nikh zhelchnokamennoi bolezniu i postkholetsistektomicheskim sindromom [Comparative study of quality of life in patients with cholelithiasis and postcholecystectomy syndrome]”. Materiali 5-go Slaviano-Baltiiskogo nauchnogo foruma «Sankt-Peterburg – Gastro-2003» [Materials of the 5th Slavic-Baltic scientific forum «Saint Petersburg-Gastro-2003»]. Gatroenterologiia Sankt-Peterburga – Gastroenterology of Saint Petersburg 2-3 (2003): 93.
  5. Maksimov VA., et al. “O vliainii gimekromona na vneshnesekretornuiu funktsiiu podzheludochnoi zhelezi u bol'nikh s postkholetsistektomicheskim sindromom [Effect of hymecromone on the external secretory function of the pancreas in patients with postcholecystectomy syndrome]”. Lechashii vrach - Attending Physician 7 (2009): 85-87.
  6. Maksimov VA., et al. “Biliarnaia nedostatochnost' [Biliary insufficiency]”. Moscow, “Adamant” Publ., (2011): 232.
  7. Mechetina TA and Il'chenko AA. “Efficacy of rifaksimin in excessive bacterial growth syndrome after cholecystectomy”. Eksperimental'naija i Klinicheskaija Gastroenterologiija 4 (2010): 100-104.
  8. Mitusheva EI., et al. “The gepatopancreatobiliary system after cholecystectomy”. Eksperimental'naija i Klinicheskaija Gastroenterologiija 9 (2015): 19-23.
  9. Mitusheva EI., et al. “Changes in gepatopancreatobiliary system organs and quality of life in patients after cholecystectomy”. Kazan Medical Journal 3 (2015): 348-353.
  10. Mitusheva EI., et al. “Pancreatic exocrine function disorders at postcholecystectomy patients”. Clinical Perspectives of Gastroenterology, Hepatology 4 (2014): 30-34.
  11. Neronov VA., et al. “Violation of the exocrine function of the liver in patients undergoing cholecystectomy”. Diary of the Kazan Medical School2 (2013): 23-28.
  12. Yakovenko EP., et al. “Disfunktsia sfinktera Oddi, sviazannaia s kholetsistektomiei [The sphincter of Oddi dysfunction related to the cholecystectomy]”. Praktikuiushii vrach – Practitioner1 (2000): 26-30.


Citation: EI Mitusheva., et al. “The State of the Organs of the Hepatopancreatobiliary System and the Quality of Life After Cholecystectomy”. Acta Scientific Gastrointestinal Disorders 4.11 (2021): 65-71.


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