Abstract

Both Diabetes mellitus (DM) and viral hepatitis are relevant when it comes to the discussion of medical and social health problems. Annually worldwide, the number of patients with type 2 diabetes mellitus (T2DM) increases by 7 million people. Hypoacid conditions and achlorhydria are noted in 60% of patients with chronic atrophic gastritis. Therefore, in addition to disorders of motor function of the stomach, patients with T2DM develop significant metabolic changes in the mucous membrane of the gastroduodenal zone. Some antioxidants are synthesized and activated by the liver, in particular transferrin, ceruloplasmin. T2DM is a manifestation of the metabolic syndrome associated with insulin resistance and is a generally accepted risk factor for non-alcoholic fatty liver disease. Increased activity of liver enzymes in the blood serum may indicate T2DM acts as extrahepatic manifestations of chronic viral hepatitis C.

Hepatitis C is one of the most dangerous liver diseases of viral etiology, the prevalence of which is growing every year. The peculiarity of chronic viral hepatitis C the presence extrahepatic manifestations. The frequency of extrahepatic manifestations in chronic hepatitis C varies from 38% to 74%.

According to modern ideas of pathogenesis, type 2 diabetes mellitus (T2DM) is considered as an extrahepatic manifestation of chronic viral hepatitis C, and chronic viral hepatitis C is considered as an etiological factor in the development of T2DM.

The prevalence of T2DM in patients with viral liver disease is 6-10 times higher than in the general population.

Many patients with extrahepatic manifestations, which are predominant in the clinical picture, may not suspect that they are carriers of viral infection HCV.

The prevalence of Iron deficiency anemia among the adult population is 2% - 6%. Recently, the relationship between iron deficiency and metabolic syndrome, prediabetes, and T2DM has been studied. Iron deficiency anemia is much more common in patients with type 2 diabetes mellitus. Iron deficiency can disrupt glucose homeostasis and therefore have a negative effect on glycemic control.

The clinical case presented in the article demonstrates the comorbidity of the lesion of the gastrointestinal tract in a patient with T2DM and is of interest to medical doctors.

Keywords: Type 2 Diabetes; Chronic Atrophic Gastritis; H. pylori; Chronic Viral Hepatitis C; Fecal Calprotectin, Fecal Elastase 1; Iron Deficiency Anemia; Sideropenic Syndrome

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Citation

Citation: Yu V Chychula. “Сlinical Case and Management of a Patient with Gastroenterological Disorders in Type 2 Diabetes Mellitus”. Acta Scientific Gastrointestinal Disorders 4.11 (2021): 43-47.

Copyright

Copyright: © 2021 Yu V Chychula. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.