Andrii I Shurma1*, Fedir V Grynchuk1 and Artem V Motric2
1Department of Surgery № 1, Bukovinian State Medical University, Chernivtsi, Ukraine
2Department of Optics and Printing, Yuriy Fedkovych Chernivtsi National University, Chernivtsi, Ukraine
*Corresponding Author: Andrii I Shurma, Department of Surgery № 1, Bukovinian State Medical University, Chernivtsi, Ukraine.
Received: September 08, 2021; Published: September 23, 2021
Citation: Andrii I Shurma., et al. “Preliminary Evaluation of Possibilities for Determination of Optical Density of Venous Blood Plasma for Diagnosis in Emergency Abdominal Surgery". Acta Scientific Gastrointestinal Disorders 4.10 (2021): 49-52.
Background/Aims: The basis of laboratory diagnosis in emergency abdominal surgery is to determine the number of leukocytes and their forms, the content of C-reactive protein. But the results of such studies are nonspecific. With unclear clinical symptoms, this creates the preconditions for diagnostic errors. Therefore, the search for new diagnostic tools that would allow for a quick, accurate assessment remains relevant. Therefore, the aim of the study was to pre-evaluate the diagnostic possibilities of determining the optical density of venous blood plasma in the infrared range for emergency abdominal surgery.
Methods: 42 patients were examined. Among them were: liver abscess - 4 cases, acute phlegmonous appendicitis with periappendicular abscess - 4, acute phlegmonous appendicitis with diffuse peritonitis - 5, acute phlegmonous appendicitis without complications - 8, acute phlegmonous cholecystitis without complications - 5, perforation of gastroduodenal ulcer with diffuse peritonitis - 5, acute adhesive intestinal obstruction without complications - 4, acute catarrhal appendicitis without complications - 3, acute catarrhal cholecystitis without complications - 4 cases.
At patients on admission to hospital venous blood from an ulnar vein was collected. Measured the optical density of venous blood plasma on a spectrophotometer SF-4A in the wavelength range l = 2.0 - 20.0 μm. The measurement results were compared with the results of the removed organs histological examination.
The control group consisted of 11 patients who had no destructive changes in organs and complications: 4 patients with adhesive intestinal obstruction, 3 patients with acute catarrhal appendicitis, 4 patients with acute catarrhal cholecystitis without complications.
Results: We found in the infrared spectrum a number of maxima of the values of the blood plasma optical density, which are localized at wavelengths l = 3.1, 3.5, 4.3, 6.1, 6.7, 9 and 17.5 μm. Indicators of optical density at these wavelengths differed in different diseases and complications.
For analysis and comparison, patients were also divided into groups: with abscesses, with diffuse peritonitis, with phlegmonous changes of organs without complications (appendicitis, cholecystitis) and control (no organ destruction). In this comparison, it was found (Figure) that at wavelengths l = 3.1, 6.1, 6.7, 9 and 17.5 μm, the optical density indices differ with specific regularities. In particular, each time in patients from the control group the parameters were statistically significantly (p < 0.05) lower than in patients with inflammatory-destructive pathology. In addition, the indicators differ in patients with diffuse peritonitis, abscesses and uncomplicated phlegmonous appendicitis and cholecystitis.
Conclusion: 1. Patients with acute surgery have specific maxima of optical density of venous blood plasma in the infrared region at wavelengths l = 3.1, 3.5, 4.3, 6.1, 6.7, 9 and 17.5 μm. 2. Indicators of optical density of blood plasma at wavelengths l = 3.1, 6.1. 6.7, 9, 17.5 microns differ, depending on features of the main disease and complications and have the general laws at perforation of hollow bodies, abscesses, diffuse peritonitis, phlegmonous changes of bodies without complications. 3. The study of optical density is a promising area for improving the diagnosis in emergency abdominal surgery.
Keywords: Emergency Abdominal Surgery; Diagnostics; Optical Density of Venous Blood Plasma
Copyright: © Andrii I Shurma., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.