Inflammatory Bowel Disease in the Elderly in the Context of COVID-19. What do we know so?
Carlos Henrique Rodrigues Castro1,2*, Caroline Rodrigues Castro1, Jackson Santos dos Reis1,2, Ewerton Naves Dias1, Claudio Roberto Tavares Pereira3, Camila Neto da Silveira4 and Luiz Ronaldo Alberti5
1Postgraduate Program in Professional Degree in Psychogerontology, Educatie School, Brazil
2Technical School Educare, Brazil
3Clinimage, Image Clinic, Brazil
4OSID - The Charitable Works Foundation of Sister Dulce, Brazil
5PhD. MSc. Doctor in Medicine, School of Medicine, Department of Surgery, Federal University of Minas Gerais, Brazil
*Corresponding Author: Carlos Henrique Rodrigues Castro, Department of Gerontology, Postgraduate Program in Professional Degree in Psychogerontology, Educatie School, Brazil.
Received: August 25, 2021; Published: September 08, 2021
Over the last few decades, several authors have demonstrated the relationship of the interaction of the immune system in a pathway called the “gut-brain axis,” with implications both for the local immune response and for the systemic modulation of inflammatory mediators. The hypothesis that the underlying inflammatory disease contributes to the pathogenesis of SARS-CoV-2, and consequently patients with inflammatory bowel disease (IBD) may theoretically be at increased risk of infection and mortality, is still controversial. With the increase in the diagnosis of IBD in patients over 60 years of age, the increased concern in the context of the SARS-CoV-2 pandemic was evident, as elderly patients have comorbidities that could raise the risk of worsening the progression of the infection and unfavorable clinical outcomes. Thus, a survey of the literature to date was carried out to understand the implications of IBD in the context of the SARS-CoV-2 pandemic.
Keywords: Elderly; Inflammatory Bowel Disease; SARS-CoV-2; COVID-19
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