Acta Scientific Gastrointestinal Disorders (ISSN: 2582-1091)

Review ArticleVolume 4 Issue 9

Should Everyone Eat Gluten-Free? What does the Scientific Data Say?

Emel Öktem Güngör* and Sevan Çetin Özbek

Department of Nutrition and Dietetics, Faculty of Health Sciences Yüksek Ihtisas University, Ankara, Turkey

*Corresponding Author: Emel Öktem Güngör, Assistant Professor, Department of Nutrition and Dietetics, Faculty of Health Sciences Yüksek Ihtisas University, Ankara, Turkey.

Received: August 23, 2021; Published: August 31, 2021

Citation: Emel Öktem Güngör and Sevan Çetin Özbek. “Should Everyone Eat Gluten-Free? What does the Scientific Data Say?". Acta Scientific Gastrointestinal Disorders 4.9 (2021): 79-84.

Abstract

  Today, changing the dietary habits of the individual to a gluten-free diet during the treatment process of Celiac disease (CD), wheat allergy (WA), non-celiac gluten sensitivity (NCGS), irritable bowel syndrome, autism, and neurological, psychiatric, and rheumatological diseases reduces the symptoms of the diseases. On the other hand, the gluten-free diet is presented as a healthy choice by the popular media. This has led to an increase in gluten-free food alternatives in the market. A long-term gluten-free diet in healthy individuals is associated with problems, such as uncontrolled weight gain, diabetes, and vitamin and mineral deficiencies. This review aims to question the effects of a gluten-free diet on health in healthy individuals. While the beneficial effects of gluten in the treatment of some diseases are supported by the literature, there is not enough evidence to support the positive effects of a gluten-free diet in healthy individuals in line with the relevant objective. Raising awareness of the community about the potential risks of adopting a gluten-free diet in individuals who do not have a gluten-related disease is possible through education emphasizing healthy and sustainable nutrition.

Keywords: Gluten; Gluten-Free Diet; Gluten-Free Diet in Individuals with no Celiac Disease; Diet Education

Bibliography

  1. Healthy Diet (2021).
  2. Melini V., et al. “Gluten-Free Diet: Gaps and Needs for a Healthier Diet”. Nutrients 1 (2019): 170.
  3. Kutlu T. “Gluten-free diet: is it really always beneficial?”. Türk Pediatri Arşivi2 (2019): 73-75.
  4. Hayıt F., et al. “Çölyak ve Çölyak Hastaları İçin Üretilen Ekmeklerin Kalite Özellikleri”. Iğdır University Journal of the Institute of Science and Technology 7 (2017): 163-169.
  5. Quan F., et al. “Gluten-Free Diet: Always as Easy, Useful, and Healthy as People Think?” Journal of Child Science 1 (2018): e75-e81.
  6. Biesiekierski JR “What is gluten?”. Journal of Gastroenterology and Hepatology 32 (2017): 78-81.
  7. Shewry P. “What Is Gluten-Why Is It Special?”. Frontiers in Nutrition 6 (2019): 101.
  8. Lerner BA., et al. “Going Against the Grains: Gluten‑Free Diets in Patients Without Celiac Disease-Worthwhile or Not?” Digestive Diseases and Sciences7 (2019): 1740-1747.
  9. Ulusoy H., et al. “Glutensiz diyetin sağlık üzerine etkileri”. Beslenme ve Diyet Dergisi2 (2019): 87-92.
  10. Wieser H. “Chemistry of glüten proteins”. Food Microbiology2 (2007): 115-119.
  11. Diez-Sampedro A., et al. “A Gluten-Free Diet, Not an Appropriate Choice without a Medical Diagnosis”. Journal of Nutrition and Metabolism (2019): 2438934.
  12. Al-Toma A., et al. “European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders”. United European Gastroenterology Journal 5 (2019): 583-613.
  13. Google (2021).
  14. Ashtari S., et al. “Prevalence of celiac disease in low and high risk population in Asia-Pacific region: a systematic review and meta‑analysis”. Scientific Reports 1 (2021): 2383.
  15. Aziz I., et al. “A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care”. European Journal of Gastroenterology and Hepatology 1 (2014): 33-39.
  16. Christoph MJ., et al. “Who values gluten-free? Dietary intake, behaviors, and sociodemographic characteristics of young adults who value gluten-free food”. Journal of the Academy of Nutrition and Dietetics8 (2018): 1389-1398.
  17. Niland B., et al. “Health Benefits and Adverse Effects of a Gluten-Free Diet in Non-Celiac Disease Patients”. Gastroenterology and Hepatology2 (2018): 82-91.
  18. Pearlman M., et al. “Who Should Be Gluten-Free? A Review for the General Practitioner”. Medical Clinics of North America1 (2019): 89-99.
  19. Aranda EA., et al. “Treating coeliac disease. How do we measure adherence to the gluten-free diet?”. Revista Chilena De Pediatria6 (2016): 442-448.
  20. Husby S., et al. “European Society for Pediatric Gastro-enterology, Hepatology, and Nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease”. Journal of Pediatric Gastroenterology and Nutrition1 (2012): 136-160.
  21. Sapone A., et al. “Spectrum of gluten-related disorders: consensus on new nomenclature and classification”. BMC Medicine 10 (2012): 13.
  22. Khoury DE., et al. “A Review on the Gluten-Free Diet: Technological and Nutritional Challenges”. Nutrients10 (2018): 1410.
  23. Codex Alimertarius İnternational Food Standards (2021).
  24. Jenkins DJ., et al. “The effect of starch-protein interaction in wheat on the glycemic response and rate of in vitro digestion”. American Journal of Clinical Nutrition 5 (2007): 946-951.
  25. Berti C., et al. “In vitro starch digestibility and in vivo glucose response of gluten-free foods and their gluten counterparts”. European Journal of Nutrition4 (2004): 198-204.
  26. Gaesser GA., et al. “Gluten-Free Diet: Imprudent Dietary Advice for the General Population?”. Journal of the Academy of Nutrition and Dietetics 9 (2012): 1329-1333.
  27. Penagini F., et al. “Gluten-free diet in children: an approach to a nutritionally adequate and balanced diet”. Nutrient11 (2013): 53-65.
  28. Neyrinck AM., et al. “Potential interest of gut microbial changes induced by nondigestible carbohydrates of wheat in the management of obesity and related disorders”. Current Opinion in Clinical Nutrition and Metabolic Care 13 (2010): 722-728.
  29. Slavin J. “Why whole grains are protective: Biological mechanisms”. Proceedings of the Nutrition Society1 (2003): 129-134.
  30. Bektaş A., et al. “Gluten: Dost mu, Düşman mı?” Güncel Gastroenteroloji 22 (2018): 127-134.
  31. De Palma G., et al. “Effects of a gluten-free diet on gut microbiota and immune function in healthy adult human subjects”. British Journal of Nutrition8 (2009): 1154-1160.
  32. Costabile A., et al. “Whole-grain wheat breakfast cereal has a prebiotic effect on the human gut microbiota: A double-blind, placebo-controlled, crossover study”. British Journal of Nutrition 1 (2008): 110-120.
  33. Behall KM., et al. “Whole-grain diets reduce blood pressure in mildly hypercholesterolemic men and women”. Journal of American Dietetic Association9 (2006): 1445-1449.
  34. Jenkins DJ., et al. “High-protein diets in hyperlipidemia: Effect of wheat gluten on serum lipids, uric acid, and renal function”. American Journal of Clinical Nutrition1 (2001): 57-63.
  35. Wu JH., et al. “Are gluten-free foods healthier than non-gluten-free foods? An evaluation of supermarket products in Australia”. British Journal of Nutrition3 (2015): 448-454.
  36. Missbach B., et al. “Gluten-free food database: the nutritional quality and cost of packaged gluten-free foods”. Peer J 3 (2015): e1337.
  37. Lebwohl B., et al. “Long term gluten consumption in adults without celiac disease and risk of coronary heart disease: prospective cohort study”. BMJ 357 (2017): 1892.
  38. Valletta E., et al. “Celiac disease and obesity: Need for nutritional follow-up after diagnosis”. European Journal of Clinical Nutrition 11 (2010): 1371-1372.
  39. Marcason W. “Is there evidence to support the claim that a gluten-free diet should be used for weight loss?” Journal of American Dietetic Association11 (2011): 1786.
  40. Cheng J., et al. “Body mass index in celiac disease. Beneficial effect of a gluten-free diet”. Journal of Clinic Gastroenterology4 (2010): 267-271.
  41. Dickey W., et al. “Overweight in celiac disease: Prevalence, clinical characteristics, and effect of a gluten-free diet”. American Journal of Gastroenterology10 (2006): 2356-2359.
  42. Lee AR., et.al. “Economic burden of a gluten-free diet”. Journal of Human Nutrition and Dietetics5 (2007): 423-430.
  43. Estevez V., et.al. “The gluten-free basic food basket: a problem of availability, cost and nutritional composition”. European Journal of Clinical Nutrition 10 (2016): 1215-1217.
  44. Singh J., et.al. “Limited availability and higher cost of gluten-free foods”. Journal of Human Nutrition and Dietetics 5 (2011): 479-486.
  45. Stevens L, et.al. “Gluten-free and regular foods: a cost comparison”. Canadian Journal of Dietetic Practice and Research3 (2008): 147-150.
  46. Global Market Insights (2021).
  47. Facts and Factors (2021).

Copyright: © Emel Öktem Güngör and Sevan Çetin Özbek. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



News and Events


  • Certification for Review
    Acta Scientific certifies the Editors/reviewers for their review done towards the assigned articles of the respective journals.
  • Submission Timeline for Upcoming Issue
    The last date for submission of articles for regular Issues is July 30, 2024.
  • Publication Certificate
    Authors will be issued a "Publication Certificate" as a mark of appreciation for publishing their work.
  • Best Article of the Issue
    The Editors will elect one Best Article after each issue release. The authors of this article will be provided with a certificate of "Best Article of the Issue"
  • Welcoming Article Submission
    Acta Scientific delightfully welcomes active researchers for submission of articles towards the upcoming issue of respective journals.

Contact US