Acta Scientific Gastrointestinal Disorders (ISSN: 2582-1091)

Short CommunicationVolume 4 Issue 8

CRISPR Genome Editing: A Boon to Medical Science

Hemshankar Laugi*

Department of Biology, Bal Kalyan Vidhya Mandir Ma. Vi., Nepal

*Corresponding Author: Hemshankar Laugi, Department of Biology, Bal Kalyan Vidhya Mandir Ma. Vi., Nepal.

Received: July 07, 2021; Published: July 20, 2021

Citation: Hemshankar Laugi. “CRISPR Genome Editing: A Boon to Medical Science”. Acta Scientific Gastrointestinal Disorders 4.8 (2021): 38-39.

  CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is one of the major discoveries in the field of medical science. It is a type of bacterial adaptive immunity used to fight against bacteriophages. It is a type of memory. Whenever a virus attacks a bacterium for the first time, it creates a memory which is used to fight with that virus if it attacks the second time. In this system, small guide RNAs (crRNAs) are employed for sequence-specific interference with invading nucleic acids. CRISPR-Cas comprises a genomic locus called CRISPR that has short repetitive elements (repeats) separated by unique sequences (spacers), which can originate from mobile genetic elements (MGEs) such as bacteriophages, transposons, or plasmids [1].


  1. Hille F and Charpentier E. “CRISPR-Cas: biology, mechanisms and relevance. Philosophical transactions of the Royal Society of London”. Series B, Biological Sciences1707 (2016): 20150496.
  2. Fineran PC and Charpentier E. “Memory of viral infections by CRISPR-Cas adaptive immune systems:acquisition of new information”. Virology 434 (2012): 202-209.
  3. Gholizadeh P., et al. “How CRISPR-Cas System Could Be Used to Combat Antimicrobial Resistance”. Infect Drug Resist 13 (2020): 1111-1121.
  4. Xu CL., et al. “Viral Delivery Systems for CRISPR”. Viruses1 (2019): 28.
  5. Montaño A., et al. “Targeted genome editing in acute lymphoblastic leukemia: a review”. BMC Biotechnology1 (2018): 45.
  6. Ayanoğlu FB., et al. “Bioethical issues in genome editing by CRISPR-Cas9 technology”. Turkish Journal of Biology = Turk Biyoloji Dergisi 2 (2020): 110-120.
  7. Maryam Mehravar., et al. “Mosaicism in CRISPR/Cas9-mediated genome editing”. Developmental Biology 2 (2019): 156-162.

Copyright: © 2021 Hemshankar Laugi. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

News and Events

Contact US