Reversal of Alcoholic Fatty Liver in Patients with Acute Pancreatitis - A Prospective Observational Study
Venkatesh Kasi Arunachalam*, Thambidurai Sadasivam, Rupa Renganathan, Gopinath Periaswamy, Haleema Sherene, Rajesh S, Rajesh Kumar Varatharajaperumal and Sriman Rajasekaran
Department of Radiology, Kovai Medical Center and Hospital, Coimbatore, India
*Corresponding Author: Venkatesh Kasi Arunachalam, Senior Consultant Radiologist, Department of Radiology, Kovai Medical Center and Hospital, Coimbatore, India.
June 17, 2021; Published: July 13, 2021
Purpose of the Study: Fatty liver is a reversible condition characterized by the accumulation of triglycerides within the hepatocytes. The prime way to reverse the fatty liver includes abstinence from alcohol, dietary modifications, and regular exercise. Our study aimed to assess the reversal of alcoholic fatty liver in patients with acute pancreatitis.
Materials and Methods: One hundred five patients with acute pancreatitis were included in our study. The liver attenuation index was calculated in a plain scan, and fatty infiltration was quantified. All the patients with fatty infiltration were divided into an alcoholic and non-alcoholic subgroup. The LAI was calculated in the follow-up CT scan in these patients with fatty infiltration, and reversal of fatty liver was calculated along with the time.
Results: Among 105 patients with acute pancreatitis, 32 had fatty liver. In these 32 patients, alcohol was the cause of acute pancreatitis in 18 patients. Follow up CT scan was done in 40 % of the patients with fatty infiltration. Out of 10 patients with fatty infiltration in an alcoholic subgroup, eight patients showed reversal of fatty liver in 4 days to 16 weeks, and all these patients were abstinent from alcohol from the time of admission.
Conclusion: Abstinence from alcohol is the mainstay in the reversal of alcoholic fatty liver, and it will take at least four weeks for the complete reversal of the alcoholic fatty liver disease.
Keywords: Alcoholic Fatty Liver; Reversal of Fatty Liver; Acute Pancreatitis; Liver Attenuation Index; Abstinence
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