Seyed Reza Fatemi¹, Naghmeh Salarieh¹*, Shabnam Shahrokh¹, Shirin Haghighi² and Seyed Ali Fatemi³

¹Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
²Departments of Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
³Life Science, Biology, student, University of Toronto, Canada

*Corresponding Author: Naghmeh Salarieh, Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Received: May 15, 2021; Published: May 27, 2021

Abstract

Duodenal carcinoids are rare form of neuroendocrine tumors with tend to invade the submucosa, during the early stages. Recently, endoscopic resection of neuroendocrine tumors of the duodenum is increasingly performed as an alternative to conventional surgery. Although, a few reports have described the use of endoscopic resection of duodenal carcinoids, it is still a challenging treatment especially for bulbar carcinoids. We performed endoscopic Sub mucosal resection (ESMR) for a case of carcinoid in posterior wall of bulb with central adhesion. Although the tumor was located in the 2^nd and submucosa layer, R0 resection was performed without complication in this case. ESMR thus is a safe and effective treatment for duodenal carcinoids less than 10 mm in diameter even with adhesion.

Keywords: Endoscopic Sub Mucosal Resection (ESMR); Duodenal Carcinoids; Neuroendocrine Tumors

References

1. Yao JC., et al. “One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States”. Journal of Clinical Oncology 26 (2008): 3063.
2. Garcia-Carbonero R., et al. “Incidence, patterns of care and prognostic factors for outcome of gastroenteropancreatic neuroendocrine tumors (GEP-NETs): results from the National Cancer Registry of Spain (RGETNE)”. Annals of Oncology 21 (2010): 1794.
3. Öberg K and Castellano D. "Current knowledge on diagnosis and staging of neuroendocrine tumors". Cancer and Metastasis Reviews 30 (2011): 3-7.
4. Gustafsson BI., et al. “Bronchopulmonary neuroendocrine tumors”. Cancer 113 (2008): 5.
5. Travis WD. “The concept of pulmonary neuroendocrine tumors”. In: Pathology and Genetics of Tumors of the Lung, Pleura, Thymus and Heart, Travis WD, et al (Eds), IARC Press, Lyon, France (2004): 19.
6. Travis WD., et al. “Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid”. The American Journal of Surgical Pathology 22 (1998): 934.
7. Moran CA and Suster S. “Neuroendocrine carcinomas (carcinoid tumor) of the thymus. A clinicopathologic analysis of 80 cases”. American Journal of Clinical Pathology 114 (2000): 10.
8. Modlin IM., et al. “Siegfried Oberdorfer: Origins and perspectives of carcinoid tumors". Human Pathology12 (2004): 1440-1451.
9. Arnold R., et al. “Chapter 15 Neuroendocrine Gastro-Entero-Pancreatic (GEP) Tumors”. In Scheppach W, Bresalier RS, Tytgat GNJ. Gastrointestinal and Liver Tumors”. Berlin: Springer (2003): 195-233.
10. Burke AP., et al. “Carcinoid tumors of the duodenum. A clinicopathologic study of 99 cases”. Archives of Pathology and Laboratory Medicine 114 (1990): 700-704.
11. Modlin IM., et al. “A 5-decade analysis of 13,715 carcinoid tumors”. Cancer 97 (2003): 934-959.
12. Burke AP., et al. “Carcinoid tumors of the duodenum. A clinicopathologic study of 99 cases”. Archives of Pathology and Laboratory Medicine 114 (1990): 700-704.
13. Yoshikane H., et al. “Carcinoid tumors of the gastrointestinal tract: evaluation with endoscopic ultrasonography”. Gastrointestinal Endoscopy 39 (1993): 375-383.
14. Nishimori I., et al. “Endosonography-guided endoscopic resection of duodenal carcinoid tumor”. Endoscopy 29 (1997): 214-217.
15. Karagiannis S., et al. “Endoscopic resection with the cap technique of a carcinoid tumor in the duodenal bulb”. Endoscopy2 (2009): E288-E289.
16. Dalenback J and Havel G. “Local endoscopic removal of duodenal carcinoid tumors”. Endoscopy 36 (2004): 651-655.
17. Jaques Waisberg., et al. The Archives of Gastroenterology1 (2013).
18. Shozo Yokoyama., et al. “Endoscopic resection of duodenal bulb neuroendocrine tumor larger than 10 mm in diameter.
19. Yuzo Otaki., et al. “Endoscopic mucosal resection with circumferential mucosal incision of duodenal carcinoid tumors”. World Journal of Gastrointestinal Endoscopy4 (2013): 197-200.
20. Hua LI., et al. “Endoscopic Mucosal Resection of Mucosal Neoplasm Located on the Duodenal Bulb through Endoscope Retroflexion (2010).

Citation

Citation: Naghmeh Salarieh., et al. “Successful Endoscopic Sub Mucosal Resection (ESMR) for Treatment of Carcinoid Tumor with Central Adhesion in Posterior Wall of Duodenum”. Acta Scientific Gastrointestinal Disorders 4.6 (2021): 70-73.

Copyright

Copyright: © 2021 Naghmeh Salarieh., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.