Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Case Report Volume 4 Issue 6

Endoscopic Diverticulectomy with Platelet-Rich Plasma of Intraluminal Duodenal Diverticulum

Vicente Lorenzo-Zúñiga1*, Vicente Moreno de Vega2 and Jaume Boix Valverde3

1Endoscopy Unit, Hospital Universitari i Politècnic La Fe, Valencia, Spain
2Endoscopy Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
3Endoscopy Unit, Hospital HM Sant Jordi, Barcelona, Spain

*Corresponding Author: Vicente Lorenzo-Zúñiga, Endoscopy Unit, Hospital Universitari i Politècnic La Fe, Valencia, Spain.

Received: March 25, 2021; Published: May 06, 2021


Background: Procedure-related bleeding remains a common complication after endoscopic diverticulectomy of intraluminal duodenal diverticulum (IDD). The optimal endoscopic approach to IDD has not been established. Platelet-rich plasma (PRP) has proven biological properties to reduce risk of bleeding.

Materials and Methods: The authors describe a novel technique in which endoscopic diverticulectomy was performed with prior submucosal injection of PRP (IRB approval PT-16-002).

Case Report: A 62-year-old woman with a large IDD like a “windsock” underwent endoscopic diverticulectomy with PRP obtained from a sample of patient’s blood. IDD was resected with EMR technique using a standard polypectomy snare. No immediate or delayed bleeding was noted. Follow-up endoscopy 3 months later revealed complete mucosal healing and open communication to the distal duodenum.

Conclusion: Endoscopic diverticulectomy with PRP is an option in patients with IDD.

Keywords: Intraluminal Duodenal Diverticulum (IDD); Platelet-Rich Plasma (PRP); Endoscopic Diverticulectomy


  1. Oukachbi N and Brouzes SJ. “Management of complicated duodenal diverticula”. Journal of Visceral Surgery 3 (2013): 173-179.
  2. Hajiro K., et al. “Endoscopic diagnosis and excision of intraluminal duodenal diverticulum”. Gastrointestinal Endoscopy 4 (1979): 151-154.
  3. Ito T., et al. “Intraluminal duodenal diverticulum with refractory pancreatitis successfully treated by endoscopic diverticulectomy”. Digestive Endoscopy 3 (2013): 336-337.
  4. Law R., et al. “Endoscopic treatment of intraluminal duodenal (“windsock”) diverticulum: varying technique from five cases”. Endoscopy12 (2012): 1161-1164.
  5. Lorenzo-Zúñiga V., et al. “Submucosal injection of platelet-rich plasma in endoscopic resection of large sessile lesions”. World Journal of Gastrointestinal Endoscopy 11 (2018): 348-353.
  6. Lorenzo-Zúñiga V., et al. “Endoscopic shielding with platelet-rich plasma after resection of large colorectal lesions”. Surgical Laparoscopy Endoscopy and Percutaneous Techniques (2020).


Citation: Vicente Lorenzo-Zúñiga., et al. “Endoscopic Diverticulectomy with Platelet-Rich Plasma of Intraluminal Duodenal Diverticulum”. Acta Scientific Gastrointestinal Disorders 4.6 (2021): 12-13.


Copyright: © 2021 Vicente Lorenzo-Zúñiga., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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