Acta Scientific Gastrointestinal Disorders (ASGIS)(ISSN: 2582-1091)

Case Report Volume 4 Issue 6

Endoscopic Diverticulectomy with Platelet-Rich Plasma of Intraluminal Duodenal Diverticulum

Vicente Lorenzo-Zúñiga1*, Vicente Moreno de Vega2 and Jaume Boix Valverde3

1Endoscopy Unit, Hospital Universitari i Politècnic La Fe, Valencia, Spain
2Endoscopy Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
3Endoscopy Unit, Hospital HM Sant Jordi, Barcelona, Spain

*Corresponding Author: Vicente Lorenzo-Zúñiga, Endoscopy Unit, Hospital Universitari i Politècnic La Fe, Valencia, Spain.

Received: March 25, 2021; Published: May 06, 2021

Abstract

Background: Procedure-related bleeding remains a common complication after endoscopic diverticulectomy of intraluminal duodenal diverticulum (IDD). The optimal endoscopic approach to IDD has not been established. Platelet-rich plasma (PRP) has proven biological properties to reduce risk of bleeding.

Materials and Methods: The authors describe a novel technique in which endoscopic diverticulectomy was performed with prior submucosal injection of PRP (IRB approval PT-16-002).

Case Report: A 62-year-old woman with a large IDD like a “windsock” underwent endoscopic diverticulectomy with PRP obtained from a sample of patient’s blood. IDD was resected with EMR technique using a standard polypectomy snare. No immediate or delayed bleeding was noted. Follow-up endoscopy 3 months later revealed complete mucosal healing and open communication to the distal duodenum.

Conclusion: Endoscopic diverticulectomy with PRP is an option in patients with IDD.

Keywords: Intraluminal Duodenal Diverticulum (IDD); Platelet-Rich Plasma (PRP); Endoscopic Diverticulectomy

References

  1. Oukachbi N and Brouzes SJ. “Management of complicated duodenal diverticula”. Journal of Visceral Surgery 3 (2013): 173-179.
  2. Hajiro K., et al. “Endoscopic diagnosis and excision of intraluminal duodenal diverticulum”. Gastrointestinal Endoscopy 4 (1979): 151-154.
  3. Ito T., et al. “Intraluminal duodenal diverticulum with refractory pancreatitis successfully treated by endoscopic diverticulectomy”. Digestive Endoscopy 3 (2013): 336-337.
  4. Law R., et al. “Endoscopic treatment of intraluminal duodenal (“windsock”) diverticulum: varying technique from five cases”. Endoscopy12 (2012): 1161-1164.
  5. Lorenzo-Zúñiga V., et al. “Submucosal injection of platelet-rich plasma in endoscopic resection of large sessile lesions”. World Journal of Gastrointestinal Endoscopy 11 (2018): 348-353.
  6. Lorenzo-Zúñiga V., et al. “Endoscopic shielding with platelet-rich plasma after resection of large colorectal lesions”. Surgical Laparoscopy Endoscopy and Percutaneous Techniques (2020).

Citation

Citation: Vicente Lorenzo-Zúñiga., et al. “Endoscopic Diverticulectomy with Platelet-Rich Plasma of Intraluminal Duodenal Diverticulum”. Acta Scientific Gastrointestinal Disorders 4.6 (2021): 12-13.

Copyright

Copyright: © 2021 Vicente Lorenzo-Zúñiga., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.




Metrics

Acceptance rate35%
Acceptance to publication20-30 days
Impact Factor0.835

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