Reza Sirous1, Raheleh Taghvaei2, Salimeh Sirous3, Mehri Sirous4, Fatemeh Dehghani Firouzabadi5, Shamila Razavi4, Farnaz Khalighi Nejad4, Vida Razavi4, Forough Yazdanian6, Saeedeh Rafiee7, Athena Farahzadi7 and Ziba Farajzadegan*8
1Department of Radiology and Nuclear Medicine, University of Maryland Medical Center-Address: 22 S Greene St, Baltimore, USA
2Department of Radiology, University of Pennsylvania- Philadelphia, USA
3Department of Surgery, Universitätsklinikum Knappschaftskrankenhaus Bochum- In der Schornau, Bochum, Germany
4Department of Radiology, Isfahan University of Medical Sciences- Hezar Jerib Ave, Isfahan, Iran
5Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
6Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran
7Minimally Invasive Surgery Research Center, Rasoul-e- Akram hospital, Iran University of Medical Sciences, Tehran, Iran
8Department of Preventive Medicine, Isfahan University of Medical Sciences- Hezar Jerib Ave, Isfahan, Iran
*Corresponding Author: Ziba Farajzadegan, Department of Preventive Medicine, Isfahan University of Medical Sciences- Hezar Jerib Ave, Isfahan, Iran. E-mail:email@example.com Department, Iran.
Received: December 23, 2020; Published: January 30, 2021
Background: Breast cancer is not only one of the most common cancers in Iran, but is also a leading cause of cancer-related mortality in Iranian women. Evidence suggests that breast cancer occurs in Iranian women 10 years earlier than their peers in developed countries. To provide reliable estimates of the incidence and trend of breast cancer in central Iran, we conducted a cross-sectional study in Isfahan Province.
Methods: We calculated the incidence and trend of breast cancer during 1980-2010 in Isfahan Province, as the most populous metropolitan city in central Iran. We conducted this cross-sectional study in four major screening mammography centers during 2012-2014 to collect data regarding the patients’ breast disease history. The final study sample consisted of 7883 women, 1275 of whom were diagnosed with breast cancer. Next, a retrospective cohort analysis was conducted on patients with breast cancer. Crude and age-standardized incidence rates (ASIR) were also calculated.
Results: During 2005-2010, ASIR was measured to be 40.4 per 100,000 person-years. The mean age of patients at the time of breast cancer diagnosis was 43.5 years (SD=8.2). The findings showed that the incidence rate of breast cancer increased steadily from 8.3 to 40.4 per 100,000 person-years from 1980 to 2010.
Conclusion: A significant increase was observed in the incidence of breast cancer, and a younger age of onset was reported in a major province over the past three decades.
Keywords: Breast Cancer; ASIR; Years of Life Lost (YLL)
Citation: Ziba Farajzadegan., et al. “Breast Cancer in Central Iran: Estimated Incidence and Trend in Isfahan Province During 30 Years”. Acta Scientific Gastrointestinal Disorders 4.2 (2021): 15-22.
Copyright: © 2021 Ziba Farajzadegan., et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.