Malaria could progress to a chronic form in individuals with partial immunity. Chronic malaria is often characterized by the lack of acute malaria symptoms. Thus, this disorder was considered as asymptomatic carrier state. Hyper-reactive malarial splenomegaly (HMS) is likely the most severe chronic form of malaria. HMS-earlier known as tropical splenomegaly syndrome - has classic manifestations. The manifestations of HMS include, massive splenomegaly, elevated titers of anti-malarial antibodies and polyclonal immunoglobulin M hypergammaglobulinemia.

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Citation

Citation: Oumer Abdu Muhie. “Hyper-Reactive Malarial Splenomegaly: A Neglected Disease by the Contemporary World”. Acta Scientific Gastrointestinal Disorders 4.1 (2020): 01-02.

Copyright

Copyright: © 2020 Oumer Abdu Muhie. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.